3-Methoxymorphinan
 | |
| Legal status | |
|---|---|
| Legal status |
|
| Identifiers | |
| CAS Number |
1531-25-5  |
| PubChem (CID) | 5484286 |
| ChemSpider |
10207434  |
| Chemical and physical data | |
| Formula | C17H23NO |
| Molar mass | 257.37 g/mol |
| |
| (what is this?) (verify) | |
3-Methoxymorphinan is a levomethorphan metabolite that has been shown to produce local anesthetic effects.[1] It is metabolized in the liver by the enzyme CYP3A4.[2]
See also
Dextrorphan | Dextromethorphan | Levomethorphan | Morphinan
References
- ↑ Hou, Chia-Hui; Tzeng, Jann-Inn; Chen, Yu-Wen; Lin, Ching-Nan; Lin, Mao-Tsun; Tu, Chieh-Hsien; Wang, Jhi-Joung (2006). "Dextromethorphan, 3-methoxymorphinan, and dextrorphan have local anaesthetic effect on sciatic nerve blockade in rats". European Journal of Pharmacology. 544 (1–3): 10–6. doi:10.1016/j.ejphar.2006.06.013. PMID 16844109.
- ↑ Min, David I.; Ku, Yi-Min; Vichiendilokkul, Aungkana; Fleckenstein, Lawrence L. (1999). "A Urine Metabolic Ratio of Dextromethorphan and 3-Methoxymorphinan as a Probe for CYP3A Activity and Prediction of Cyclosporine Clearance in Healthy Volunteers". Pharmacotherapy. 19 (6): 753–9. doi:10.1592/phco.19.9.753.31536. PMID 10391422.
This article is issued from Wikipedia - version of the 8/24/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.