BD-1047

BD-1047
Clinical data

ATC code	none
Identifiers
IUPAC name N'-[2-(3,4-dichlorophenyl)ethyl]-N,N,N'-trimethylethane-1,2-diamine
CAS Number	138356-20-4^N
PubChem (CID)	188914
IUPHAR/BPS	6680
ChemSpider	164154^Y
ChEMBL	CHEMBL143360^Y
Chemical and physical data
Formula	C₁₃H₂₀Cl₂N₂
Molar mass	275.217 g/mol
3D model (Jmol)	Interactive image
SMILES Clc1ccc(CCN(C)CCN(C)C)cc1Cl
InChI InChI=1S/C13H20Cl2N2/c1-16(2)8-9-17(3)7-6-11-4-5-12(14)13(15)10-11/h4-5,10H,6-9H2,1-3H3^Y Key:MGVRNMUKTZOQOW-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

BD-1047 is a sigma receptor antagonist, selective for the σ₁ subtype. It has effects in animal studies suggestive of antipsychotic activity and may also be useful in the treatment of neuropathic pain.^[1]^[2]

References

↑ Skuza G, Rogóz Z (2006). "Effect of BD 1047, a sigma1 receptor antagonist, in the animal models predictive of antipsychotic activity". Pharmacological Reports : PR. 58 (5): 626–35. PMID 17085854.
↑ Roh DH, Kim HW, Yoon SY, Seo HS, Kwon YB, Kim KW, Han HJ, Beitz AJ, Na HS, Lee JH (November 2008). "Intrathecal injection of the sigma(1) receptor antagonist BD1047 blocks both mechanical allodynia and increases in spinal NR1 expression during the induction phase of rodent neuropathic pain". Anesthesiology. 109 (5): 879–89. doi:10.1097/ALN.0b013e3181895a83. PMID 18946301.

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