Benzoxepin

Benzoxepin is an oxygen-containing heterocycle consisting of a Oxepin ring and a benzene ring. There are three isomers:

1-benzoxepin 2-benzoxepin 3-benzoxepin

The bicyclic ringsystem of the benzoxepins is part of certain naturally occurring compounds. E.g. Perilloxin (I) from Perilla frutescens (variant Acuta),[1] and Tenual (II) and Tenucarb (III) from Asphodeline tenuior.[2]

References

  1. J. Liu, A. Steigel, E. Reininger, R. Bauer (2000), "Two New Prenylated 3-Benzoxepin Derivatives as Cyclooxygenase Inhibitors from Perilla frutescens var. acuta", J. Nat. Prod., 63 (3): 403–405, doi:10.1021/np990362o
  2. A. Ulubelen, E. Tuzlaci, N. Atilan (1989), "Oxepine derivatives and anthraquinones from Asphodeline tenuior and A. Taurica", Phytochem., 28 (2): 649–650, doi:10.1016/0031-9422(89)80076-7


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