Butamben

Butamben
Clinical data

AHFS/Drugs.com	Micromedex Detailed Consumer Information
Routes of administration	Topical
ATC code	none
Identifiers
IUPAC name Butyl 4-aminobenzoate
Synonyms	n-butyl p-aminobenzoate
CAS Number	94-25-7^Y
PubChem (CID)	2482
ChemSpider	2388^Y
UNII	EFW857872Q^Y
KEGG	D00730
ChEBI	CHEBI:3231
ChEMBL	CHEMBL127516^Y
ECHA InfoCard	100.002.107
Chemical and physical data
Formula	C₁₁H₁₅NO₂
Molar mass	193.242 g/mol
3D model (Jmol)	Interactive image
Melting point	58 °C (136 °F)
SMILES O=C(OCCCC)c1ccc(N)cc1
InChI InChI=1S/C11H15NO2/c1-2-3-8-14-11(13)9-4-6-10(12)7-5-9/h4-7H,2-3,8,12H2,1H3^Y Key:IUWVALYLNVXWKX-UHFFFAOYSA-N^Y
(verify)

Butamben is a local anesthetic. It is the ester of 4-aminobenzoic acid and butanol.^[1] A white, odourless, crystalline powder. that is mildy soluble in water (1 part in 7000) and soluble in alcohol, ether, chloroform, fixed oils, and dilute acids. It slowly hydrolyses when boiled with water. Synonyms include Butamben, Butilaminobenzoato, and Butoforme. Proprietary names includes Alvogil in Spain and Alvogyl in Switzerland. It is one of three components in the topical anesthetic Cetacaine.

References

↑ drugs.com Butamben

Local anesthetics (primarily sodium channel blockers) (N01B)

Esters by acid

Aminobenzoic	Benzocaine Butacaine Butamben Chloroprocaine Dimethocaine Lucaine Meprylcaine Metabutethamine Metabutoxycaine Nitracaine Orthocaine Propoxycaine Procaine (Novocaine) Proxymetacaine Risocaine Tetracaine

Benzoic	Amylocaine Cocaine Cyclomethycaine α-Eucaine β-Eucaine Hexylcaine Isobucaine Piperocaine

ArCO2- (not para-amino or Ph)	Amoproxan (3,4,5-Trimethoxybenzoyl) 3-(p-Fluorobenzoyloxy)tropane

Amides

Articaine
Bupivacaine^# / Levobupivacaine / Ropivacaine
Butanilicaine
Carticaine
Dibucaine
Etidocaine
Lidocaine^#
Mepivacaine
Prilocaine
Trimecaine

Combinations

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

This article is issued from Wikipedia - version of the 4/2/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.