Calyculin
![]() Calyculins A and C | |
Identifiers | |
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ChEMBL | ChEMBL384277 ![]() |
ChemSpider | 9084513 (Calyculin A) ![]() |
PubChem | 10909255 (Calyculin A) |
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Properties | |
C51H83N4O15P (Calyculin C) | |
Molar mass | 1023.2 g/mol (Calyculin C) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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Infobox references | |
Calyculins are natural products originally isolated from the marine sponge Discodermia calyx.[1] Calyculins have proven to be strong serine/threonine protein phosphatase inhibitors and based on this property, calyculins might be potential anticancer agents.
References
- ↑ Suganuma M, Fujiki H, Furuya-Suguri H, Yoshizawa S, Yasumoto S, Kato Y, Fusetani N, Sugimura T (1990). "Calyculin A, an inhibitor of protein phosphatases, a potent tumor promoter on CD-1 mouse skin". Cancer Res. 50 (12): 3521–3525.
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