Gefarnate

Gefarnate
Skeletal formula
Space-filling model
Clinical data
AHFS/Drugs.com International Drug Names
ATC code A02BX07 (WHO)
Identifiers
CAS Number 51-77-4 YesY
PubChem (CID) 5282182
ChemSpider 4445377 N
UNII 1ISE2Y6ULA YesY
KEGG D01529 YesY
ChEMBL CHEMBL2105085 N
ECHA InfoCard 100.000.111
Chemical and physical data
Formula C27H44O2
Molar mass 400.637 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Gefarnate is a drug used for the treatment of gastric ulcers.[1]

It also has been proposed for use in the treatment of dry eye syndrome.[2][3]

References

  1. Ohta Y, Kobayashi T, Imai Y, Inui K, Yoshino J, Nakazawa S (August 2005). "Effect of gefarnate on acute gastric mucosal lesion progression in rats treated with compound 48/80, a mast cell degranulator, in comparison with that of teprenone". Biol. Pharm. Bull. 28 (8): 1424–30. doi:10.1248/bpb.28.1424. PMID 16079487.
  2. Peral A, Domínguez-Godínez CO, Carracedo G, Pintor J (April 2008). "Therapeutic targets in dry eye syndrome". Drug News Perspect. 21 (3): 166–76. PMID 18560615.
  3. Gipson IK, Hori Y, Argüeso P (April 2004). "Character of ocular surface mucins and their alteration in dry eye disease". Ocul Surf. 2 (2): 131–48. doi:10.1016/s1542-0124(12)70149-0. PMID 17216084.


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