Germinal matrix

In anatomy, the germinal matrix is a highly cellular and highly vascularized region in the brain from which cells migrate out during brain development. The germinal matrix is the source of both neurons and glial cells and is most active between 8 and 28 weeks gestation. It is a fragile portion of the brain that may be damaged leading to an intracranial hemorrhage known as a germinal matrix hemorrhage.

Location/Anatomy: The germinal matrix is next to the lateral ventricles (the "inside" of the brain).

Function/Physiology: Neurons and glia migrate radially outward from the germinal matrix towards the cerebral cortex. For more information, see the associated articles on neuronal migration and corticogenesis.

Dysfunction/Pathophysiology: in prenatology/neonatology, intraventricular hemorrhages occur starting in the germinal matrix due to the lack of structural integrity there. Intraventricular hemorrhages are a common and harmful issue in children born prematurely.

External links

Ultrasound Pictures of Germinal Matrix IVH MedPix Image Database

Development of the nervous system

Neurogenesis

General	Neural development Neurulation Neurula Notochord Neuroectoderm Neural plate Neural fold Neural groove Neuropoiesis Adult neurogenesis

Neural crest	Cranial neural crest Cardiac neural crest complex Truncal neural crest

Neural tube	Rostral neuropore Neuromere / Rhombomere Cephalic flexure Pontine flexure Alar plate Basal plate Glioblast Neuroblast Germinal matrix

Eye

Ear

Otic placode
- Otic pit
- Otic vesicle

This article is issued from Wikipedia - version of the 4/6/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.

Germinal matrix

See also

External links