Higouménakis' sign

Higouménakis' sign^[1] is a unilateral enlargement of the sternoclavicular portion of the clavicle, seen in congenital syphilis. It is an end result of neonatal periostitis.

This sign was first described by George Higoumenakis in 1927 in the Greek periodical Proceedings of the Medical Society of Athens (Πρακτικά Ιατρικής Εταιρείας Αθηνών).^[2] He subsequently published the description of the sign in a German article, making the sign more known among dermatologists.^[3] Thus, the sign was named after George Higoumenakis.

See also

• List of cutaneous conditions

References

1. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
2. Higoumenakis G: A new stigma of hereditary syphilis. Proceedings of the Medical Society of Athens. 687-699 (1927).
3. Higoumenakis, G. K. (September 1930). "Neues Stigma der kongenitalen Lues". Deutsche Zeitschrift für Nervenheilkunde. 114 (4-6): 288–299. doi:10.1007/BF01652813.

Bibliography

• Higoumenakis KG: Higoumenakis's sign and its significance for the diagnosis of congenital syphilis. Dermatologische Wochenschrift 154(30):697-705 (1968).
• Higoumenakis G: A new stigma of hereditary syphilis. Proceedings of the Medical Society of Athens. 687-699 (1927). [in Greek]
• Higoumenakis G: Neues Stigma der kongenitalen Lues. Die Vergrößerung des sternalen Endes des Rechten Schlüsselbeins, seine Beschreibung, Deutung and Ätiologie. Deutsche Zeitschrift für Nervenheilkunde. 114(4):288-299 (1930).
• Frangos CC, Frangos CC: George Higoumenakis (1895–1983): Greek dermatologist. Journal of Medical Biography 17(2):64-72 (2009).
• Frangos CC, Frangos CC: George Higoumenakis (1895–1983), Dermatologist: The Tale of 'Higoumenakis Sign' in Congenital Syphilis and His Life Achievements. Analecta Historico Medica (Supplement 1-part III):133-137 (2008).
• Φράγκος ΚΧ: Γέωργιος Κ. Ηγουμενάκης. BioMedResearch.gr, Ιούνιος 2009.