Howard Green (physician)

Howard Green
Born (1925-09-10)September 10, 1925
Toronto
Died October 13, 2015(2015-10-13) (aged 90)
Boston, Massachusetts
Institutions New York University School of Medicine,
Massachusetts Institute of Technology,
Harvard Medical School
Alma mater University of Toronto
Known for stem-cell research, skin culture
Influences James G. Rheinwald,
Burton D. Goldberg,
Susan Schlegel,
John B. Mulliken
Nicholas O’Connor
Notable awards March of Dimes Prize in Developmental Biology
Spouse Rosine Kauffmann

Howard Green (September 10, 1925 – October 31, 2015) was an American scientist, and George Higginson Professor of Cell Biology at Harvard Medical School.

He was the first to culture human cells in a laboratory setting for therapeutic use. He is one of the founding fathers of stem-cell research and regenerative medicine.[1][2]

Education and Personal Life

Howard Green was born in 1925 in Toronto, Ontario. He graduated from University of Toronto medical school. He served in the United States Army. He taught at New York University School of Medicine, Massachusetts Institute of Technology from 1970 to 1980, and Harvard Medical School from 1980 to 1993.[3]

Green married Rosine Kauffmann Green née Kauffmann in 1954.[4]

He died on October 31, 2015, outside Boston, Massachusetts.

On November 23, 2016, Shriner's Hospitals for Children in Boston announced the opening of the Howard Green Center for Children's Skin Health and Research, funded by a $3 million gift from his wife, Mrs. Rosine Kauffmann Green.[5][6]

Academic Positions Held

Harvard Medical School

George Higginson Professor of Cell Biology

Chairman - Department of Cellular and Molecular Physiology 1980-1993

Head of Green Lab

Massachusetts Institute of Technology

Professor of Cell Biology[7]

New York University School of Medicine

Faculty member of the Department of Pathology[7]

Awards and Honors

Award Year
March of Dimes Prize in Developmental Biology[8][9][10] 2012
Warren Alpert Foundation Prize[11] 2010
Blaise Pascal Award in Medical and Life Sciences of the European Academy of Sciences[12] 2007
Legion of Honour[13] 2001
Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research[14] 1979
Member, National Academy of Sciences[15] 1978

Publications

Book

Therapy with Cultured Cells - book published 2010[16]

Selected Academic Articles

Date Title Journal
May 1, 1963 The Growth of Mouse Embryo Cells In Culture and Their Development into Established Lines [17] The Journal of Cell Biology
November 1975 Serial Cultivation of Strains of Human Epidermal Keratinocytes: The Formation of Keratinzing Colonies from Single Cells[18] Cell
November 1979 Growth of cultured human epidermal cells into multiple epithelia suitable for grafting[19] Proceedings of the National Academy of Sciences of the United States of America
January 10, 1981 Grafting of Burns with Cultured Epithelium Prepared from Autologous Epidermal Cells[20] The Lancet

References

  1. "Howard Green". www.warrenalpert.org. Retrieved 2015-10-18.
  2. "Howard Green, Who Found a Way to Grow Skin and Saved Lives, Dies at 90". The New York times. November 5, 2015.
  3. Roberts, Sam (2015-11-05). "Howard Green, Who Found a Way to Grow Skin and Saved Lives, Dies at 90". The New York Times. ISSN 0362-4331. Retrieved 2015-12-17.
  4. "Howard Green dies at 90; Harvard scientist developed technique for regenerating human skin". latimes.com. Retrieved 2015-12-17.
  5. "The Howard Green Center for Children's Skin Health and Research is dedicated to advancing the field of regenerative medicine.". www.shrinershospitalsforchildren.org. Retrieved 2016-02-25.
  6. "Shriners Hospitals for Children". www.shrinershospitalsforchildren.org. Retrieved 2016-02-25.
  7. 1 2 "Howard Green Department of Pathology". www.med.nyu.edu. Retrieved 2015-10-17.
  8. "March of Dimes" (PDF). March of Dimes - Prize Award Recipient History. March of Dimes. Retrieved 2015-10-17.
  9. "March of Dimes Awards $250,000 Prize to Two Scientists Who Pioneered Advances in Skin Disorders | March of Dimes". www.marchofdimes.org. Retrieved 2015-10-17.
  10. "Harvard biologist Dr. Howard Green's $250,000 prize - The Boston Globe". BostonGlobe.com. Retrieved 2015-10-17.
  11. "Prize Recipients | warrenalpert.org". www.warrenalpert.org. Retrieved 2015-10-17.
  12. "European Academy of Sciences - Blaise Pascal Medals 2007". www.eurasc.org. Retrieved 2015-10-17.
  13. "DR. HOWARD GREEN's Obituary on". Boston Globe. Retrieved 2015-12-17.
  14. "Past Winners | Rosenstiel Award | Rosenstiel Basic Medical Sciences Research Center | Brandeis University". www.brandeis.edu. Retrieved 2015-10-18.
  15. "Howard Green". www.nasonline.org. Retrieved 2015-10-17.
  16. Green, Howard (2010-03-31). Therapy with Cultured Cells (1 ed.). Singapore: Pan Stanford. ISBN 9789814267700.
  17. Green, Howard (May 1, 1963). "QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES" (PDF). The Journal of Cell Biology. Retrieved 2015-10-17.
  18. Green, Howard (November 1975). "Serial Cultivation of Strains of Human Keratinocytes: the Formation of Keratinizing Colonies from Single Cells" (PDF). Cell. 6: 331–343. doi:10.1016/s0092-8674(75)80001-8. Retrieved 2015-10-17.
  19. Green, Howard (November 1979). "Growth of cultured human epidermal cells into multiple epithelia suitable for grafting" (PDF). Proceedings of the National Academy of Sciences of the United States of America. 76: 5665–5668. doi:10.1073/pnas.76.11.5665. Retrieved 2015-10-17.
  20. "GRAFTING OF BURNS WITH CULTURED EPITHELIUM PREPARED FROM AUTOLOGOUS EPIDERMAL CELLS". The Lancet. 317: 75–78. doi:10.1016/S0140-6736(81)90006-4. Retrieved 2015-10-18.
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