Methade

Methade

Names
IUPAC name 6-(dimethylamino)-4,4-diphenylheptane
Identifiers
3D model (Jmol)	Interactive image
InChI InChI=MCFVCWVAZLRHPN-UHFFFAOYSA-N Key: 1S/C21H29N/c1-5-16-21(17-18(2)22(3)4,19-12-8-6-9-13-19)20-14-10-7-11-15-20/h6-15,18H,5,16-17H2,1-4H3
SMILES CN(C(CC(CCC)(C1=CC=CC=C1)C2=CC=CC=C2)C)C
Properties
Chemical formula	C21H29N
Molar mass	295.4668 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Methade, or 6-(dimethylamino)-4,4-diphenylheptane, is the parent compound of the methadone and methadol series of opioid analgesics:^[1]

Chemical derivatives

The methade series includes the following compounds:

• Acetylmethadol
  • Alphacetylmethadol
    • Levacetylmethadol
  • Betacetylmethadol)
• Dimepheptanol (or methadol)
  • Alphamethadol
  • Betamethadol
• Methadone
  • Levomethadone
• Noracymethadol
• Normethadone

Related compounds

Some related compounds include:

• Alimadol
• Dextromoramide
• Dextropropoxyphene
• Dipipanone
• Isomethadone
• Normethadone
• Norpipanone
• Phenadoxone

References

1. Perrine TD, May EL (1954). "Synthesis of 6-dimethylamino-4,4-diphenyl-heptane and other compounds related to methadone". Journal of Organic Chemistry. American Chemical Society. 19 (5): 773–779. doi:10.1021/jo01370a012. ISSN 1520-6904.