Monica Riley
Monica Riley | |
---|---|
Born | 1926 |
Died |
October 11, 2013 Richmond, California |
Monica Riley (1926 - October 11, 2013) was an American scientist who contributed to the discovery of messenger RNA in her Ph.D work with Arthur Pardee, and was later a pioneer in the exploration and computer representation of the Escherichia coli genome.
After graduating Smith College with a chemistry degree in 1947, she studied Biochemistry at University of California Berkeley with Pardee.[1][2] Her Ph.D. work, together with the PaJaMo experiment, ruled out ribosomes as carriers of information to synthesize protein, leading the discovery of messenger RNA.[3] After holding faculty positions at University of California Davis and SUNY Stony Brook, she moved to the Marine Biological Laboratory in Woods Hole, staying there until age 80.[2] During this time, she helped launch the EcoCyc database of Escherichia coli metabolism[4] and developed classification systems for genes and proteins which were forerunners of gene ontology.[1][2]
References
- 1 2 Olena, Abby (November 7, 2013). "Genomics Pioneer Dies". The Scientist.
- 1 2 3 Serres, Greta. "Monica Riley (1926 - 2013)".
- ↑ Crick , Francis (1988). What Mad Pursuit. pp. 118–119.
- ↑ Karp, Peter; Riley, Monica; Paley, Suzanne M.; Pelligrini-Toole, Alida. "EcoCyc: an encyclopedia of Escherichia coli genes and metabolism". Nucleic Acids Research. 24 (1): 32–39. doi:10.1093/nar/24.1.32. PMC 145574. PMID 8594595.