PME
PME may refer to:
- Particle mesh Ewald, an algorithm used in calculating electrostatic forces in molecular dynamics simulations in computational biology and physics
- Physical Medium Entity, an abstract defined by IEEE 802.3 standard
- Pi Mu Epsilon is the U.S. national mathematics honor society
- Pointsec Media Encryption, now owned by Check Point Software Technologies Ltd.
- Power Management Event (computing) is a PCI connector pin
- Premature Ejaculation
- Professional Military Education
- Progressive myoclonus epilepsies
- Protective Multiple Earthing the TN–C–S type of Earthing system
- Pacific Mozart Ensemble
- Personal Mobile Electronics
- Public Market Equivalent is a measure of historical performance of private equity
- P.M.E., clerical abbreviation for the members of the Roman Catholic Société des Missions-Étrangères du Québec
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