Pinaverium

Pinaverium

Clinical data
ATC code	A03AX04 (WHO)
Identifiers
IUPAC name 4-(2-bromo-4,5-dimethoxybenzyl)-4-(2-[2-(6,6-dimethylbicyclo[3.1.1]heptan-2-yl)ethoxy]ethyl)morpholin-4-ium
CAS Number	59995-65-2
PubChem (CID)	40704
ChemSpider	37182
Chemical and physical data
Formula	C26H41BrNO4
Molar mass	511.51 g/mol
3D model (Jmol)	Interactive image
SMILES CC1(C2CCC(C1C2)CCOCC[N+]3(CCOCC3)CC4=CC(=C(C=C4Br)OC)OC)C
InChI InChI=1S/C26H41BrNO4/c1-26(2)21-6-5-19(22(26)16-21)7-11-31-12-8-28(9-13-32-14-10-28)18-20-15-24(29-3)25(30-4)17-23(20)27/h15,17,19,21-22H,5-14,16,18H2,1-4H3/q+1 Key:DDHUTBKXLWCZCO-UHFFFAOYSA-N
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Pinaverium is a drug used for functional gastrointestinal disorders. It belongs to a drug group call antispasmodic and acts as a calcium channel blocker in helping to restore the normal contraction process of the bowel. It is most effective when taken for a full course of treatment and is not designed for immediate symptom relief or sporadic, intermittent use.

Pinaverium was first registered in 1975 and is currently marketed in over 60 countries in the trade names Dicetel and Eldicet. The branded version was discovered and manufactured by Solvay Pharmaceuticals, currently Abbott Laboratories.

It is available in South Korea under a trade name of Disten.^[1]

Indications

It is indicated for the treatment and relief of symptoms associated with irritable bowel syndrome (IBS): abdominal pain, bowel disturbances and intestinal discomfort; and treatment of symptoms related to functional disorders of biliary tract.^[2]

References

1. KMLE 약품/의약품 정보: 디스텐정 (Disten Tab.) Hangul: 
2. Abbott Laboratories (Feb 2012). Dicetel Product Insert/Information Malaysia.