Pteridine

Names

IUPAC name

pteridine

Identifiers

CAS Number

91-18-9^Y

3D model (Jmol)

CHEBI:27601^N

1014^N

C07581^N

6EZF26XQ81^Y

InChI=1S/C6H4N4/c1-2-9-6-5(8-1)3-7-4-10-6/h1-4H^N
Key: CPNGPNLZQNNVQM-UHFFFAOYSA-N^N
InChI=1/C6H4N4/c1-2-9-6-5(8-1)3-7-4-10-6/h1-4H
Key: CPNGPNLZQNNVQM-UHFFFAOYAU

SMILES

C1=CN=C2C(=N1)C=NC=N2

Properties

Chemical formula

C₆H₄N₄

Molar mass

132.13 g·mol⁻¹

Melting point

139.5 °C

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

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Infobox references

Pteridine is an aromatic chemical compound composed of fused pyrimidine and pyrazine rings. A pteridine is also a group of heterocyclic compounds containing a wide variety of substitutions on this structure. Pterins and flavins are classes of substituted pteridines that have important biological activity.

Pteridine is a precursor in the synthesis of dihydrofolic acid in many microorganisms. The enzyme dihydropteroate synthetase converts pteridine and 4-aminobenzoic acid to dihydrofolic acid in the presence of glutamate. The enzyme dihydropteroate synthetase is inhibited by sulfonamide antibiotics.

References

Voet, D.; Voet, J.G. (2004). Biochemistry (3rd ed.). John Wiley & Sons. ISBN 0-471-39223-5

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Pteridine

See also

References