Quassin
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| Names | |
|---|---|
| IUPAC name
2,12-dimethoxypicrasa-2,12-diene-1,11,16-trione | |
| Other names
(3aS,6aR,7aS,8S,11aS,11bS,11cS) -1,3a,4,5,6a,7,7a,8,11,11a,11b,11c-dodecahydro-2,10-dimethoxy-3,8,11a,11c- tetramethyldibenzo[de,g]chromene-1,5,11-trione | |
| Identifiers | |
76-78-8  | |
| 3D model (Jmol) | Interactive image |
| ChEMBL | ChEMBL517016  |
| ChemSpider | 59014 |
| ECHA InfoCard | 100.000.897 |
| EC Number | 200-985-9 |
| PubChem | 65571 |
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| |
| Properties | |
| C22H28O6 | |
| Molar mass | 388.46 g·mol−1 |
| Appearance | White crystalline substance |
| Melting point | 200 to 222 °C (392 to 432 °F; 473 to 495 K) |
| Boiling point | 586 °C (1,087 °F; 859 K) |
| Insoluble | |
| Vapor pressure | 13 mmHg (@25 °C) |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| verify (what is ?) | |
| Infobox references | |
Quassin is a white bitter, crystalline substance extracted from the quassia tree, isolated in 1937 and elucidated in 1961. It is the It is one of the most bitter substances found in nature with a bitter threshold of 0.08 ppm and it is 50 times more bitter than quinine.[1]
Quassin is used as a medicine in traditional Chinese medicine.
Extracts of the Bitter tree (or bitter wood) (Quassia amara L. or Picrasma excelsa) are also used as additives in soft drinks.[1]
Although its skeleton possesses 20 carbon atoms, quassin is not a diterpene but rather a triterpene lactone, which derives from euphol by loss of 10 carbon atoms including C4.
References
- 1 2 Scientific Committee on Food Opinion of the Scientific Committee on Food on quassin (expressed on 2 July 2002). SCF/CS/FLAV/FLAVOUR/29 Final
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