Residual ovary syndrome

Residual ovary syndrome
Classification and external resources
ICD-10 N99.8
ICD-9-CM 629

Residual ovary syndrome or ovarian remnant syndrome[1] is a condition that occurs when ovarian tissue is left behind following oophorectomy, causing development of a pelvic mass, pelvic pain, and occasionally dyspareunia.[2][3][4] The frequency is about 1.8% in spayed female dogs.

Clinic

In the female, it is diagnosed if permanent or recurring abdominal pain manifests. Urinary problems, weakness, fever, nausea, vaginal bleeding and pain during bowel movements may also occur.

In female dogs and queens a heat or heat cycle occurs despite spaying as in intact animals. Females often develop pseudopregnancy or pyometra. In addition, in female dogs from ovary remains a granulosa cell tumour with Läufigkeitssymptomen, accretion of the mammary glands, skin problems, bone marrow suppression and endometrial hyperplasia develops. Overall, the syndrome is more common in cats than in dogs, and it is almost exclusively due to surgical errors (incomplete ovariectomy), ectopic tissue is very rare.

Diagnostics

Remnant tissue can be seen by ultrasonography or magnetic resonance imaging, optionally after administration of Clomifene 10 days before the examination.

Laboratory diagnosis are primarily elevated levels of estrogen or progesterone corresponding to the normal sexual cycle.

The measurement of estrogens is not practical in veterinary medicine, their effect can, however, by means of vaginal cytology be detected. Alternatively, the progesterone levels can be measured 5 to 7 days after suspected ovulation can be measured. If necessary, the ovulation may with hCG or GnRH be triggered. Progesterone levels above 2 ng / ml (6.4 nmol / L) are conclusive for the presence of corpus luteum, and thus hormonally active ovarian tissue.

Therapy

The therapy consists of surgical removal of the residual tissue.

The operation should be performed in dogs and cats during the hormonally active phase (heat or metestrus done), because the ovarian tissue is easier to find then, due to the ovarian follicles or Corpus luteum.

References

  1. John F. Steege, MD. "What is ovarian remnant syndrome?". HealthyWomen. National Women's Health Resource Center, Inc. Retrieved 1 April 2014.
  2. Christ, JE; Lotze, EC (November 1975). "The residual ovary syndrome.". Obstetrics and gynecology. 46 (5): 551–6. PMID 1196557.
  3. Hwu, YM; Wu, CH; Yang, YC; Wang, KG (May 1989). "The residual ovary syndrome.". Zhonghua yi xue za zhi = Chinese medical journal; Free China ed. 43 (5): 335–40. PMID 2804789.
  4. Dekel, A; Efrat, Z; Orvieto, R; Levy, T; Dicker, D; Gal, R; Ben-Rafael, Z (September 1996). "The residual ovary syndrome: a 20-year experience.". European journal of obstetrics, gynecology, and reproductive biology. 68 (1-2): 159–64. doi:10.1016/0301-2115(96)00250-3. PMID 8886700.
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