Salicylanilide

Salicylanilide^[1]

Names
IUPAC name 2-Hydroxy-N-phenylbenzamide
Other names 2-Hydroxybenzanilide
Identifiers
CAS Number	87-17-2
3D model (Jmol)	Interactive image
ChemSpider	6610
ECHA InfoCard	100.001.571
PubChem	6872
UNII	LHP8NEY345
InChI InChI=1S/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16) Key: WKEDVNSFRWHDNR-UHFFFAOYSA-N InChI=1/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16) Key: WKEDVNSFRWHDNR-UHFFFAOYAI
SMILES C1=CC=C(C=C1)NC(=O)C2=CC=CC=C2O
Properties
Chemical formula	C13H11NO2
Molar mass	213.24 g·mol^−1
Appearance	White to off-white crystalline solid
Melting point	136 to 138 °C (277 to 280 °F; 409 to 411 K)
Hazards
EU classification (DSD)	Xi
R-phrases	R36/37/38
S-phrases	S36/37/39
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Salicylanilide is a chemical compound which is the amide of salicylic acid and aniline. It is classified as both a salicylamide and an anilide.^[2]

Derivatives of salicylanilide have a variety of pharmacological uses. Chlorinated derivatives including niclosamide, oxyclozanide, and rafoxanide are used as anthelmintics, especially as flukicides. Brominated derivatives including dibromsalan, metabromsalan, and tribromsalan are used as disinfectants with antibacterial and antifungal activities.

• 
  Bromochlorosalicylanilide
• 
  Niclosamide
• 
  Oxyclozanide
• 
  Rafoxanide

Uses

Salicylanilides may be used as antiseptics.

References

1. Salicylanilide at chemicalland21.com
2. Salicylanilides at the US National Library of Medicine Medical Subject Headings (MeSH)