Suplatast tosilate
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Clinical data | |
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AHFS/Drugs.com | International Drug Names |
Routes of administration | Oral |
ATC code | none |
Legal status | |
Legal status |
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Identifiers | |
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CAS Number |
94055-76-2 ![]() |
PubChem (CID) | 71773 |
UNII |
C9J89787U1 ![]() |
KEGG |
D01423 ![]() |
ChEMBL |
CHEMBL115435 ![]() |
ECHA InfoCard | 100.220.132 |
Chemical and physical data | |
Formula | C23H33NO7S2 |
Molar mass | 499.64 g/mol |
3D model (Jmol) | Interactive image |
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Suplatast tosilate (INN) is a Th2 cytokine inhibitor[1] which is used as an antiallergic drug. Often used in the treatment of Kimura's disease.[2][3]
References
- ↑ Tamaoki J, Kondo M, Sakai N, et al. (July 2000). "Effect of suplatast tosilate, a Th2 cytokine inhibitor, on steroid-dependent asthma: a double-blind randomised study. Tokyo Joshi-Idai Asthma Research Group". Lancet. 356 (9226): 273–8. doi:10.1016/S0140-6736(00)02501-0. PMID 11071181.
- ↑ Ueda T, Arai S, Amoh Y, Katsuoka K (2011). "Kimura's disease treated with suplatast tosilate and loratadine". European Journal of Dermatology. 21 (6): 1020–1. doi:10.1684/ejd.2011.1539. PMID 21914581.
- ↑ Tsukagoshi H, Nagashima M, Horie T, et al. (December 1998). "Kimura's disease associated with bronchial asthma presenting eosinophilia and hyperimmunoglobulinemia E which were attenuated by suplatast tosilate (IPD-1151T)". Internal Medicine. 37 (12): 1064–7. doi:10.2169/internalmedicine.37.1064. PMID 9932643.
Further reading
- Taniguchi H, Togawa M, Ohwada K, et al. (December 1996). "Suplatast tosilate, a new type of antiallergic agent, prevents the expression of airway hyperresponsiveness in guinea pigs". European Journal of Pharmacology. 318 (2-3): 447–54. doi:10.1016/S0014-2999(96)00810-2. PMID 9016937.
- Sano Y (December 1996). "[Anti-inflammatory drugs for the treatment of bronchial hyperresponsiveness]". Nihon Kyōbu Shikkan Gakkai Zasshi (in Japanese). 34 Suppl: 48–53. PMID 9216184.
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