XanPHol family

The Xanthomonas Phage Holin (XanPHol) Family (TC# 1.E.45) consists of a single protein (Putative holin; TC# 1.E.45.1.1) of 64 amino acyl residues (aas) in length with 2 transmembrane segments (TMSs). It is a putative uncharacterized protein from Xanthomonas phage Xp15. This protein corresponds to sequence 68 from patent US 7919601 ('Identification and use of genes encoding holins and holin-like proteins in plants for the control of microbes and pests').^[1] As of March 2016, this protein does not show appreciable sequence similarity to any other proteins in the NCBI protein database.^[2][3]

See also

• Holin
• Lysin
• Transporter Classification Database

Further reading

• Reddy, Bhaskara L.; Saier Jr, Milton H. (2013). "Topological and phylogenetic analyses of bacterial holin families and superfamilies". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1828 (11): 2654–2671. doi:10.1016/j.bbamem.2013.07.004. PMC 3788059. PMID 23856191.
• Saier, Milton H.; Reddy, Bhaskara L. (2015). "Holins in Bacteria, Eukaryotes, and Archaea: Multifunctional Xenologues with Potential Biotechnological and Biomedical Applications". Journal of Bacteriology. 197 (1): 7–17. doi:10.1128/JB.02046-14. PMC 4288690. PMID 25157079.
• Wang, I. N.; Smith, D. L.; Young, R. (2000). "Holins: the protein clocks of bacteriophage infections". Annual Review of Microbiology. 54: 799–825. doi:10.1146/annurev.micro.54.1.799. PMID 11018145.
• Young, R; Bläsi, U (1995). "Holins: form and function in bacteriophage lysis". FEMS Microbiol. Rev. 17: 191–205. doi:10.1111/j.1574-6976.1995.tb00202.x. PMID 7669346.

References

1. Ramadugu, Chandrika; Gabriel, Dean William (Apr 5, 2011), Identification and use of genes encoding holins and holin-like proteins in plants for the control of microbes and pests, retrieved 2016-03-29
2. "BLAST: Basic Local Alignment Search Tool". blast.ncbi.nlm.nih.gov. Retrieved 2016-03-29.
3. "1.E.45 The Xanthomonas Phage Holin (XanPHol) Family". TCDB. Retrieved 2016-03-29.

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