AMICA1

JAML
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3MJ6, 3MJ7, 3MJ9
Identifiers
Aliases	JAML, AMICA, CREA7-1, CREA7-4, Gm638, AMICA1, junction adhesion molecule like
External IDs	MGI: 2685484 HomoloGene: 17708 GeneCards: JAML
Gene ontology Molecular function • integrin binding • protein homodimerization activity • cell adhesion molecule binding Cellular component • integral component of membrane • cell junction • plasma membrane • membrane • bicellular tight junction Biological process • immune system process • gamma-delta T cell activation • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules • monocyte extravasation • neutrophil extravasation • cell adhesion • positive regulation of epithelial cell proliferation involved in wound healing • leukocyte migration • neutrophil chemotaxis • regulation of immune response Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	120425	270152
Ensembl	ENSG00000160593	ENSMUSG00000048534
UniProt	Q86YT9	Q80UL9
RefSeq (mRNA)	NM_001098526 NM_001286570 NM_001286571 NM_153206	NM_001005421
RefSeq (protein)	NP_001091996.1 NP_001273499.1 NP_001273500.1 NP_694938.2	NP_001005421.3
Location (UCSC)	Chr 11: 118.19 – 118.23 Mb	Chr 9: 45.08 – 45.11 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Junctional adhesion molecule-like is a protein that in humans is encoded by the AMICA1 gene.^[3][4]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A (Oct 2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
4. "Entrez Gene: AMICA1 adhesion molecule, interacts with CXADR antigen 1".

Further reading

• Kimura K; Wakamatsu A; Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Zen K; Liu Y; McCall IC; et al. (2005). "Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial coxsackie and adenovirus receptor and a junctional adhesion molecule-like protein on neutrophils". Mol. Biol. Cell. 16 (6): 2694–703. doi:10.1091/mbc.E05-01-0036. PMC 1142417. PMID 15800062.
• Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
• Ota T; Suzuki Y; Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Moog-Lutz C; Cavé-Riant F; Guibal FC; et al. (2004). "JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells". Blood. 102 (9): 3371–8. doi:10.1182/blood-2002-11-3462. PMID 12869515.
• Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Dias Neto E; Correa RG; Verjovski-Almeida S; et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.