CDCA3

CDCA3
Identifiers
Aliases	CDCA3, GRCC8, TOME-1, cell division cycle associated 3
External IDs	MGI: 1315198 HomoloGene: 8403 GeneCards: CDCA3
Gene ontology Molecular function • molecular function • protein binding Cellular component • cytosol • cytoplasm • cellular component • cell-cell junction Biological process • biological process • cell division • cell cycle • mitotic nuclear division • protein ubiquitination Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	83461	14793
Ensembl	ENSG00000111665	ENSMUSG00000023505
UniProt	Q99618	Q99M54
RefSeq (mRNA)	NM_001297602 NM_001297603 NM_001297604 NM_031299	NM_013538
RefSeq (protein)	NP_001284531.1 NP_001284532.1 NP_001284533.1 NP_112589.1	NP_038566.1
Location (UCSC)	Chr 12: 6.84 – 6.85 Mb	Chr 6: 124.83 – 124.83 Mb
PubMed search	[1]	[2]
Wikidata

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Cell division cycle-associated protein 3 is a protein that in humans is encoded by the CDCA3 gene.^[3][4][5]

Interactions

CDCA3 has been shown to interact with SKP1A.^[6]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Ansari-Lari MA, Shen Y, Muzny DM, Lee W, Gibbs RA (May 1997). "Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination". Genome Res. 7 (3): 268–80. doi:10.1101/gr.7.3.268. PMID 9074930.
4. Walker MG (Aug 2002). "Drug target discovery by gene expression analysis: cell cycle genes". Curr Cancer Drug Targets. 1 (1): 73–83. doi:10.2174/1568009013334241. PMID 12188893.
5. "Entrez Gene: CDCA3 cell division cycle associated 3".
6. Ayad, Nagi G; Rankin Susannah; Murakami Monica; Jebanathirajah Judith; Gygi Steven; Kirschner Marc W (Apr 2003). "Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC". Cell. United States. 113 (1): 101–13. doi:10.1016/S0092-8674(03)00232-0. ISSN 0092-8674. PMID 12679038.

Further reading

• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Yoshida K (2005). "Cell-cycle-dependent regulation of the human and mouse Tome-1 promoters.". FEBS Lett. 579 (6): 1488–92. doi:10.1016/j.febslet.2005.01.055. PMID 15733861.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Ayad NG, Rankin S, Murakami M, et al. (2003). "Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC.". Cell. 113 (1): 101–13. doi:10.1016/S0092-8674(03)00232-0. PMID 12679038.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ansari-Lari MA, Muzny DM, Lu J, et al. (1996). "A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13.". Genome Res. 6 (4): 314–26. doi:10.1101/gr.6.4.314. PMID 8723724.