CENTB1

ACAP1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3JUE, 3T9K, 4CKG, 4CKH, 4F1P, 4NSW
Identifiers
Aliases	ACAP1, CENTB1, ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
External IDs	MGI: 2388270 HomoloGene: 22835 GeneCards: ACAP1
Gene ontology Molecular function • protein binding • metal ion binding • GTPase activator activity Cellular component • endosome • recycling endosome membrane • membrane Biological process • protein transport • positive regulation of GTPase activity • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	9744	216859
Ensembl	ENSG00000072818	ENSMUSG00000001588
UniProt	Q15027	Q8K2H4
RefSeq (mRNA)	NM_014716	NM_153788
RefSeq (protein)	NP_055531.1	NP_722483.2
Location (UCSC)	Chr 17: 7.34 – 7.35 Mb	Chr 11: 69.88 – 69.9 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 is a protein that in humans is encoded by the ACAP1 gene.^[3][4][5]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Jackson TR, Kearns BG, Theibert AB (Dec 2000). "Cytohesins and centaurins: mediators of PI 3-kinase-regulated Arf signaling". Trends Biochem Sci. 25 (10): 489–95. doi:10.1016/S0968-0004(00)01644-3. PMID 11050434.
4. Jackson TR, Brown FD, Nie Z, Miura K, Foroni L, Sun J, Hsu VW, Donaldson JG, Randazzo PA (Nov 2000). "ACAPs are arf6 GTPase-activating proteins that function in the cell periphery". J Cell Biol. 151 (3): 627–38. doi:10.1083/jcb.151.3.627. PMC 2185579. PMID 11062263.
5. "Entrez Gene: CENTB1 centaurin, beta 1".

Further reading

• Nomura N, Nagase T, Miyajima N, et al. (1995). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.". DNA Res. 1 (5): 223–9. doi:10.1093/dnares/1.5.223. PMID 7584044.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Dai J, Li J, Bos E, et al. (2004). "ACAP1 promotes endocytic recycling by recognizing recycling sorting signals.". Dev. Cell. 7 (5): 771–6. doi:10.1016/j.devcel.2004.10.002. PMID 15525538.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Zhan X, Desiderio DM (2006). "Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry.". Anal. Biochem. 354 (2): 279–89. doi:10.1016/j.ab.2006.05.024. PMID 16777052.
• Yamamoto-Furusho JK, Barnich N, Xavier R, et al. (2007). "Centaurin beta1 down-regulates nucleotide-binding oligomerization domains 1- and 2-dependent NF-kappaB activation.". J. Biol. Chem. 281 (47): 36060–70. doi:10.1074/jbc.M602383200. PMID 17005562.
• Shinozaki-Narikawa N, Kodama T, Shibasaki Y (2007). "Cooperation of phosphoinositides and BAR domain proteins in endosomal tubulation.". Traffic. 7 (11): 1539–50. doi:10.1111/j.1600-0854.2006.00480.x. PMID 17010122.
• Li J, Peters PJ, Bai M, et al. (2007). "An ACAP1-containing clathrin coat complex for endocytic recycling.". J. Cell Biol. 178 (3): 453–64. doi:10.1083/jcb.200608033. PMC 2064835. PMID 17664335.