CLEC9A

CLEC9A
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3VPP
Identifiers
Aliases	CLEC9A, DNGR1, UNQ9341, CD370, DNGR-1, C-type lectin domain family 9 member A
External IDs	MGI: 2444608 HomoloGene: 52106 GeneCards: CLEC9A
Gene ontology Molecular function • carbohydrate binding Cellular component • integral component of membrane • cell surface • membrane Biological process • positive regulation of cytokine secretion • endocytosis • receptor-mediated endocytosis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	283420	232414
Ensembl	ENSG00000197992	ENSMUSG00000046080
UniProt	Q6UXN8	Q8BRU4
RefSeq (mRNA)	NM_207345	NM_001205363 NM_001205364 NM_001205365 NM_172732
RefSeq (protein)	NP_997228.1	NP_001192292.1 NP_001192293.1 NP_001192294.1 NP_766320.2
Location (UCSC)	Chr 12: 10.03 – 10.07 Mb	Chr 6: 129.41 – 129.42 Mb
PubMed search	[1]	[2]
Wikidata

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C-type lectin domain family 9 member A is a protein that in humans is encoded by the CLEC9A gene. ^[3]

Function

CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. "Entrez Gene: C-type lectin domain family 9 member A". Retrieved 2016-06-02.

Further reading

• Huysamen C, Willment JA, Dennehy KM, Brown GD (2008). "CLEC9A is a novel activation C-type lectin-like receptor expressed on BDCA3+ dendritic cells and a subset of monocytes". J. Biol. Chem. 283 (24): 16693–701. doi:10.1074/jbc.M709923200. PMC 2562446. PMID 18408006.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.