Dieter Seebach

Dieter Seebach
Born	31 October 1937 Karlsruhe, Germany
Nationality	German
Institutions	University of Karlsruhe (TH) University of Giessen ETH Zurich
Alma mater	University of Karlsruhe (TH) Harvard University
Doctoral advisor	Rudolf Criegee
Doctoral students	Dieter Enders, Paul Knochel
Influenced	Elias James Corey
Notable awards	Marcel Benoist Prize (2000) The Ryoji Noyori Prize (2004)

Dieter Seebach is a German chemist known for his synthesis of biopolymers and dendrimers, and for his contributions to stereochemistry. He was born on 31 October 1937 in Karlsruhe. He studied chemistry at the University of Karlsruhe (TH) under the supervision of Rudolf Criegee and at Harvard University with Elias Corey finishing in 1969. After his habilitation he became professor for organic chemistry at the University of Giessen. After six years he was appointed professor at the ETH Zurich where he worked until he retired in 2003.

Work

He works on dendrimer chemistry and on the synthesis of beta-peptides.^[1][2] The development of the umpolung, a polarity inversion of the carbonyl group, with 1,3-propanedithiol together with Corey had a big influence on organic synthesis.^[3]

The Fráter–Seebach alkylation, a diastereoselective reaction of beta-hydroxy esters, is named after him.

Awards

• 2000 Marcel Benoist Prize
• 2003 Tetrahedron Prize for Creativity in Organic Chemistry & BioMedicinal Chemistry
• 2004 The Ryoji Noyori Prize

References

1. Hook, David F. (2004). "Celebrating Dieter Seebach's Contributions to Science: A Bitter Sweet Occasion?". Chimia. 58 (2): 321–324. doi:10.2533/000942904777677876.
2. Dieter Seebach and Jennifer L. Matthews (1997). "β-Peptides: a surprise at every turn". Chem. Commun. (21): 2015–2022. doi:10.1039/a704933a.
3. Seebach D., Corey E. J. (1975). "Generation and synthetic applications of 2-lithio-1,3-dithianes". Journal of Organic Chemistry. 40 (2): 231–237. doi:10.1021/jo00890a018.

External links

• Article on Seebach from 2003
• Seebach homepage at ETH