Dextranomer

Dextranomer
Clinical data
Trade names Debrisan
AHFS/Drugs.com International Drug Names
Routes of
administration
Topical
ATC code D03AX02 (WHO)
Identifiers
CAS Number 56087-11-7 N
PubChem (SID) 214362
ChemSpider none
ECHA InfoCard 100.128.106
 NYesY (what is this?)  (verify)

Dextranomer (trade name Debrisan) is a cicatrizant used in dressings for wound healing,[1] and in pharmaceutical products to treat fecal incontinence.[2] It consists of dextran polymer chains cross-linked into a three-dimensional network.[3]

Solesta

Solesta is the marketed brand name of a system of injections of dextranomer in stabilized sodium hyaluronate for use in fecal incontinence (FI).[4] This preparation is a biocompatible gel, for use as a perianal injectable bulking agent. The system is intended to be injected in the submucosal layer of the proximal anal canal (i.e. above the level of the dentate line).

References

  1. Parulkar BG, Sobti MK, Pardanani DS (1985). "Dextranomer dressing in the treatment of infected wounds and cutaneous ulcers". J Postgrad Med. 31 (1): 28–33.
  2. Solesta Gel Approved for Fecal Incontinence
  3. Solesta Package Insert
  4. Hoy, SM (Aug 20, 2012). "Dextranomer in stabilized sodium hyaluronate (Solesta): in adults with faecal incontinence.". Drugs. 72 (12): 1671–8. doi:10.2165/11209030-000000000-00000. PMID 22845415.


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