FDX1L

FDX1L
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2Y5C
Identifiers
Aliases	FDX1L, FDX2, ferredoxin 1 like
External IDs	MGI: 1915415 HomoloGene: 31955 GeneCards: FDX1L
Gene ontology Molecular function • iron-sulfur cluster binding • protein binding • metal ion binding • 2 iron, 2 sulfur cluster binding • electron carrier activity Cellular component • mitochondrial matrix • mitochondrion Biological process • C21-steroid hormone biosynthetic process • sterol metabolic process • oxidation-reduction process • small molecule metabolic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	112812	68165
Ensembl	ENSG00000267673	ENSMUSG00000079677
UniProt	Q6P4F2	Q9CPW2
RefSeq (mRNA)	NM_080665 NM_001031734	NM_001039824
RefSeq (protein)	NP_001026904.2	NP_001034913.1
Location (UCSC)	Chr 19: 10.31 – 10.32 Mb	Chr 9: 21.07 – 21.07 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Ferredoxin 1-like is a protein that in humans is encoded by the FDX1L gene.^[3]

Mutations in FDX1L cause mitochondrial myopathy .^[4]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. "Entrez Gene: Ferredoxin 1-like".
4. Spiegel R, Saada A, Halvardson J, Soiferman D, Shaag A, Edvardson S, Horovitz Y, Khayat M, Shalev SA, Feuk L, Elpeleg O (July 2014). "Deleterious mutation in FDX1L gene is associated with a novel mitochondrial muscle myopathy". European Journal of Human Genetics. 22 (7): 902–6. doi:10.1038/ejhg.2013.269. PMID 24281368.

Further reading

• Sheftel AD, Stehling O, Pierik AJ, Elsässer HP, Mühlenhoff U, Webert H, Hobler A, Hannemann F, Bernhardt R, Lill R (June 2010). "Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis". Proceedings of the National Academy of Sciences of the United States of America. 107 (26): 11775–80. doi:10.1073/pnas.1004250107. PMC 2900682. PMID 20547883.