Fleischer ring
Fleischer rings are pigmented rings in the peripheral cornea, resulting from iron deposition[1] in basal epithelial cells, in the form of hemosiderin.[2] They are usually yellowish to dark-brown, and may be complete or broken.
They are named for Bruno Fleischer.[3]
Fleischer rings are indicative of keratoconus,[4] a degenerative corneal condition that causes the cornea to thin and change to a conic shape.
Confusion with Kayser-Fleischer rings
Some confusion exists between Fleischer rings and Kayser-Fleischer rings. Kayser-Fleischer rings are caused by copper deposits, and are indicative of Wilson's disease, whereas Fleischer rings are caused by iron deposits. One example of a medical condition that can present with Fleischer rings is Keratoconus.
See also
Other iron lines:
- Hudson–Stahli line, associated with aging
- Limbal ring
References
- ↑ "Cornea & External Diseases-Keratoconus Fleischer's Ring". Retrieved 2008-10-24.
- ↑ "Definition: Fleischer's ring from Online Medical Dictionary". Retrieved 2008-10-24.
- ↑ Fleischer, B (1906). "Über Keratokonus und eigenartige Pigmentbildung in der Kornea". Münchener medizinische Wochenschrift. 53: 625–626.
- ↑ Hiratsuka Y, Nakayasu K, Kanai A (2000). "Secondary keratoconus with corneal epithelial iron ring similar to Fleischer's ring". Japanese Journal of Ophthalmology. 44 (4): 381–6. doi:10.1016/S0021-5155(00)00179-9. PMID 10974294.
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