Fustin

Fustin

Names
IUPAC name 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-2,3-dihydrochromen-4-one
Other names Dihydrofisetin Tetrahydroxyflavanone 3,7,3',4'-Tetrahydroxyflavanone 2,3-Dihydrofisetin 3′,4′,7-trihydroxyflavanol
Identifiers
CAS Number	20725-03-5
3D model (Jmol)	Interactive image
ECHA InfoCard	100.039.975
PubChem	5317435
SMILES C1=CC(=C(C=C1C2C(C(=O)C3=C(O2)C=C(C=C3)O)O)O)O
Properties
Chemical formula	C15H12O6
Molar mass	288.25 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Fustin, sometimes called "dihydrofisetin", is a flavan-on-ol, a type of flavonoid. It can be found in young fustic (Cotinus coggygria)^[1] and in the lacquer tree^[2] (Toxicodendron vernicifluum, aka Rhus verniciflua).

Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death.^[2]

Unlike Fisetin, fustin has no double bond in the C-ring. This makes fustin a flavan, with two stereocenters and four stereoisomers.

References

1. Phytochemical analysis of young fustic (Cotinus coggygria heartwood) and identification of isolated colourants in historical textiles, Lemonia Valianou, Konstantina Stathopoulou, Ioannis Karapanagiotis, Prokopios Magiatis, Eleni Pavlidou, Alexios-Leandros Skaltsounis and Yannis Chryssoulakis, 2009
2. Protective effects of fustin, a flavonoid from Rhus verniciflua Stokes, on 6-hydroxydopamine-induced neuronal cell death. Park BC, Lee YS, Park HJ, Kwak MK, Yoo BK, Kim JY, Kim JA. 2007