H2AFV

H2AFV
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases H2AFV, H2A.Z-2, H2AV, H2A histone family member V
External IDs MGI: 1924855 HomoloGene: 83271 GeneCards: H2AFV
RNA expression pattern




More reference expression data
Orthologs
Species Human Mouse
Entrez

94239

77605

Ensembl

ENSG00000105968

ENSMUSG00000041126

UniProt

Q71UI9

Q3THW5

RefSeq (mRNA)

NM_201517
NM_012412
NM_138635
NM_201436
NM_201516

NM_029938

RefSeq (protein)

NP_036544.1
NP_619541.1
NP_958844.1
NP_958924.1
NP_958925.1

NP_084214.1

Location (UCSC) Chr 7: 44.83 – 44.85 Mb Chr 11: 6.43 – 6.44 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Histone H2A.V is a protein that in humans is encoded by the H2AFV gene.[3]

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. Several transcripts have been identified for this gene.[3]

References

Further reading


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