HLA-B55

major histocompatibility complex (human), class I, B55
Alleles B*5501, B*5502
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*5501
B*5502
Locus chr.6 6p21.31

HLA-B55 (B55) is an HLA-B serotype. B55 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B56. The serotype identifies the more common HLA-B*55 gene products.[1] (For terminology help see: HLA-serotype tutorial)

Serotype

B55 and B22 serotype recognition of some HLA B*55 allele-group gene products[2]
B*55 B55 B22 Sample
allele % % size (N)
5501 92 5 453
5502 84 2 309

Allele distribution

HLA B*5501 frequencies
freq
ref. Population (%)
[3] India New Delhi3.8
[3] Singapore Chinese Han3.5
[3] Spain Eastern Andalusia Gipsy3.5
[3] Georgia Tibilisi Kurds3.4
[3] India North Delhi3.3
[3] France South East3.1
[3] Israel Arab Druse3.0
[3] India North Hindus2.9
[3] Georgia Tibilisi Georgians2.8
[3] Russia Tuva (2)2.8
[3] Georgia Svaneti Svans2.5
[3] Iran Baloch2.5
[3] Singapore Thai2.5
[3] Sudanese2.5
[3] Mexico Mestizos2.4
[3] Spain Eastern Andalusia2.4
[3] Ireland South2.0
[3] Azores Central Islands1.8
[3] Bulgaria1.8
[3] Israel Ashkenazi and Non Ashkenazi Jews1.8
[3] Oman1.7
[3] Tunisia Tunis1.7
[3] India Andhra Pradesh Golla1.4
[3] China Tibet1.3
[3] Uganda Kampala1.2
[3] Finland1.1
[3] Portugal North1.1
[3] Portugal Centre1.0
[3] Singapore Riau Malay1.0
[3] B*5502
[3] Taiwan Taroko14.5
[3] American Samoa12.0
[3] China Guangxi Maonan6.0
[3] Japan Ainu Hokkaido5.0
[3] China Tibet Autonomous Region Tibetans4.7
[3] Singapore Chinese3.0
[3] China Beijing Shijiazhuang Tianjian Han2.9
[3] China North Han2.9
[3] South Korea (3)2.7
[3] Hong Kong Chinese2.2
[3] Japan (5)2.2
[3] Taiwan Ami2.0
[3] Thailand (3)2.0
[3] New Caledonia1.0
[3] Philippines Ivatan1.0

References

  1. Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
  2. derived from IMGT/HLA
  3. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. External link in |title= (help)
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