Isopropamide
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Clinical data | |
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MedlinePlus | a694006 |
Routes of administration | Oral |
ATC code | A03AB09 (WHO) |
Legal status | |
Legal status |
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Identifiers | |
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CAS Number |
7492-32-2 ![]() |
PubChem (CID) | 3775 |
DrugBank |
DB01625 ![]() |
ChemSpider |
3643 ![]() |
UNII |
8B9I31H724 ![]() |
ChEMBL |
CHEMBL1201232 ![]() |
ECHA InfoCard | 100.028.470 |
Chemical and physical data | |
Formula | C23H33N2O+ |
Molar mass | 353.52092 g/mol |
3D model (Jmol) | Interactive image |
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Isopropamide (R5) is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility. Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt. It was discovered at Janssen Pharmaceutica in 1954.
References
- Seeherman R, Isopropamide iodide: a long-acting anticholinergic, Del Med J. 1957 Oct;29(10):265-9.
- Boss EG Jr, Buchanan GC, Effect of isopropamide iodide on basal gastric secretion in the human, Gastroenterology. 1957 Nov;33(5):730-6.
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