PDZK1IP1

PDZK1IP1
Identifiers
Aliases	PDZK1IP1, DD96, MAP17, SPAP, PDZK1 interacting protein 1
External IDs	MGI: 1914432 HomoloGene: 4213 GeneCards: PDZK1IP1
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	10158	67182
Ensembl	ENSG00000162366	ENSMUSG00000028716
UniProt	Q13113	Q9CQH0
RefSeq (mRNA)	NM_005764	NM_001164557 NM_001164558 NM_026018
RefSeq (protein)	NP_005755.1	NP_001158029.1 NP_001158030.1 NP_080294.1
Location (UCSC)	Chr 1: 47.18 – 47.19 Mb	Chr 4: 115.09 – 115.09 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

PDZK1-interacting protein 1 is a protein that in humans is encoded by the PDZK1IP1 gene.^{[3][4][5][6][7]}

Interactions

PDZK1IP1 has been shown to interact with PDZK1.^[5][6][8]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Kocher O, Cheresh P, Brown LF, Lee SW (Feb 1999). "Identification of a novel gene, selectively up-regulated in human carcinomas, using the differential display technique". Clin. Cancer Res. 1 (10): 1209–15. PMID 9815914.
4. Kocher O, Cheresh P, Lee SW (Sep 1996). "Identification and partial characterization of a novel membrane-associated protein (MAP17) up-regulated in human carcinomas and modulating cell replication and tumor growth". Am. J. Pathol. 149 (2): 493–500. PMC 1865305. PMID 8701988.
5. Silver DL, Wang N, Vogel S (Jul 2003). "Identification of small PDZK1-associated protein, DD96/MAP17, as a regulator of PDZK1 and plasma high density lipoprotein levels". J. Biol. Chem. 278 (31): 28528–32. doi:10.1074/jbc.M304109200. PMID 12754212.
6. Pribanic S, Gisler SM, Bacic D, Madjdpour C, Hernando N, Sorribas V, Gantenbein A, Biber J, Murer H (Sep 2003). "Interactions of MAP17 with the NaPi-IIa/PDZK1 protein complex in renal proximal tubular cells". Am. J. Physiol. Renal Physiol. 285 (4): F784–91. doi:10.1152/ajprenal.00109.2003. PMID 12837682.
7. "Entrez Gene: PDZK1IP1 PDZK1 interacting protein 1".
8. Gisler SM, Pribanic S, Bacic D, Forrer P, Gantenbein A, Sabourin LA, Tsuji A, Zhao ZS, Manser E, Biber J, Murer H (Nov 2003). "PDZK1: I. a major scaffolder in brush borders of proximal tubular cells". Kidney Int. 64 (5): 1733–45. doi:10.1046/j.1523-1755.2003.00266.x. PMID 14531806.

Further reading

• Kocher O, Comella N, Tognazzi K, Brown LF (1998). "Identification and partial characterization of PDZK1: a novel protein containing PDZ interaction domains". Lab. Invest. 78 (1): 117–25. PMID 9461128.
• Göttgens B, Barton LM, Chapman MA, Sinclair AM, Knudsen B, Grafham D, Gilbert JG, Rogers J, Bentley DR, Green AR (2002). "Transcriptional regulation of the stem cell leukemia gene (SCL)--comparative analysis of five vertebrate SCL loci". Genome Res. 12 (5): 749–59. doi:10.1101/gr.45502. PMC 186570. PMID 11997341.
• Gisler SM, Pribanic S, Bacic D, Forrer P, Gantenbein A, Sabourin LA, Tsuji A, Zhao ZS, Manser E, Biber J, Murer H (2003). "PDZK1: I. a major scaffolder in brush borders of proximal tubular cells". Kidney Int. 64 (5): 1733–45. doi:10.1046/j.1523-1755.2003.00266.x. PMID 14531806.
• Guijarro MV, Castro ME, Romero L, Moneo V, Carnero A (2007). "Large scale genetic screen identifies MAP17 as protein bypassing TNF-induced growth arrest". J. Cell. Biochem. 101 (1): 112–21. doi:10.1002/jcb.21163. PMID 17230460.
• Guijarro MV, Leal JF, Fominaya J, Blanco-Aparicio C, Alonso S, Lleonart M, Castellvi J, Ruiz L, Ramon y Cajal S, Carnero A (2007). "MAP17 overexpression is a common characteristic of carcinomas". Carcinogenesis. 28 (8): 1646–52. doi:10.1093/carcin/bgm083. PMID 17426052.
• Guijarro MV, Leal JF, Blanco-Aparicio C, Alonso S, Fominaya J, Lleonart M, Castellvi J, Ramon y Cajal S, Carnero A (2007). "MAP17 enhances the malignant behavior of tumor cells through ROS increase". Carcinogenesis. 28 (10): 2096–104. doi:10.1093/carcin/bgm124. PMID 17548903.

External links

• PDZK1IP1 human gene location in the UCSC Genome Browser.
• PDZK1IP1 human gene details in the UCSC Genome Browser.