PHLDB1
| PHLDB1 | ||||||
|---|---|---|---|---|---|---|
| Identifiers | ||||||
| Aliases | PHLDB1, LL5A, pleckstrin homology like domain family B member 1 | |||||
| External IDs | MGI: 2143230 HomoloGene: 15903 GeneCards: PHLDB1 | |||||
| Genetically Related Diseases | ||||||
| glioma[1] | ||||||
| RNA expression pattern | ||||||
 | ||||||
| More reference expression data | ||||||
| Orthologs | ||||||
| Species | Human | Mouse | ||||
| Entrez | ||||||
| Ensembl | ||||||
| UniProt | ||||||
| RefSeq (mRNA) | ||||||
| RefSeq (protein) | ||||||
| Location (UCSC) | Chr 11: 118.61 – 118.66 Mb | Chr 9: 44.69 – 44.74 Mb | ||||
| PubMed search | [2] | [3] | ||||
| Wikidata | ||||||
| View/Edit Human | View/Edit Mouse |
Pleckstrin homology-like domain family B member 1 is a protein that in humans is encoded by the PHLDB1 gene.[4][5]
The first PHLDB1 cDNA was cloned from a rat pituitary cDNA library and named as LL5 after the clone number.[6]
References
- ↑ "Diseases that are genetically associated with PHLDB1 view/edit references on wikidata".
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ Katoh M, Katoh M (Oct 2003). "Identification and characterization of human LL5A gene and mouse Ll5a gene in silico". Int J Oncol. 23 (5): 1477–83. doi:10.3892/ijo.23.5.1477. PMID 14532993.
- ↑ "Entrez Gene: PHLDB1 pleckstrin homology-like domain, family B, member 1".
- ↑ Levi L, Hanukoglu I, Raikhinstein M, Kohen F, Koch Y (16 November 1993). "Cloning of LL5, a novel protein encoding cDNA from a rat pituitary library.". Biochimica et biophysica acta. 1216 (2): 342–4. doi:10.1016/0167-4781(93)90171-9. PMID 8241284.
Further reading
- Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (June 2002). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
- Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (June 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
- Dowler S, Currie RA, Campbell DG, Deak M, Kular G, Downes CP, Alessi DR (October 2000). "Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities". Biochem. J. 351 (Pt 1): 19–31. doi:10.1042/0264-6021:3510019. PMC 1221362
. PMID 11001876. - Hotta A, Kawakatsu T, Nakatani T, Sato T, Matsui C, Sukezane T, Akagi T, Hamaji T, Grigoriev I, Akhmanova A, Takai Y, Mimori-Kiyosue Y (May 2010). "Laminin-based cell adhesion anchors microtubule plus ends to the epithelial cell basal cortex through LL5alpha/beta". J. Cell Biol. 189 (5): 901–17. doi:10.1083/jcb.200910095. PMC 2878951. PMID 20513769.
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