PIK3AP1

PIK3AP1
Identifiers
Aliases	PIK3AP1, BCAP, phosphoinositide-3-kinase adaptor protein 1
External IDs	MGI: 1933177 HomoloGene: 12848 GeneCards: PIK3AP1
Gene ontology Molecular function • phosphatidylinositol 3-kinase regulatory subunit binding • identical protein binding Cellular component • cytoplasm • cytosol • plasma membrane • membrane Biological process • positive regulation of phosphatidylinositol 3-kinase signaling • toll-like receptor 9 signaling pathway • positive regulation of toll-like receptor signaling pathway • toll-like receptor 2 signaling pathway • negative regulation of toll-like receptor signaling pathway • toll-like receptor 4 signaling pathway • toll-like receptor 7 signaling pathway • regulation of inflammatory response Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	118788	83490
Ensembl	ENSG00000155629	ENSMUSG00000025017
UniProt	Q6ZUJ8	Q9EQ32
RefSeq (mRNA)	NM_152309	NM_031376
RefSeq (protein)	NP_689522.2	NP_113553.1
Location (UCSC)	Chr 10: 96.59 – 96.72 Mb	Chr 19: 41.27 – 41.39 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Phosphoinositide 3-kinase adapter protein 1 is an enzyme that in humans is encoded by the PIK3AP1 gene.^[3][4][5]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Edwards JA, Sethi PK, Scoma AJ, Bannerman RM, Frohman LA (Apr 1976). "A new familial syndrome characterized by pigmentary retinopathy, hypogonadism, mental retardation, nerve deafness and glucose intolerance". Am J Med. 60 (1): 23–32. doi:10.1016/0002-9343(76)90529-5. PMID 1251844.
4. Okada T, Maeda A, Iwamatsu A, Gotoh K, Kurosaki T (Jan 2001). "BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation". Immunity. 13 (6): 817–27. doi:10.1016/S1074-7613(00)00079-0. PMID 11163197.
5. "Entrez Gene: PIK3AP1 phosphoinositide-3-kinase adaptor protein 1".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Maruoka M, Suzuki J, Kawata S, et al. (2005). "Identification of B cell adaptor for PI3-kinase (BCAP) as an Abl interactor 1-regulated substrate of Abl kinases". FEBS Lett. 579 (14): 2986–90. doi:10.1016/j.febslet.2005.04.052. PMID 15893754.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.