PRKRIR

THAP12
Identifiers
Aliases THAP12, DAP4, P52rIPK, THAP0, PRKRIR, THAP domain containing 12
External IDs MGI: 1920231 HomoloGene: 37952 GeneCards: THAP12
Orthologs
Species Human Mouse
Entrez

5612

72981

Ensembl

ENSG00000137492

ENSMUSG00000030753

UniProt

O43422

Q9CUX1

RefSeq (mRNA)

NM_004705

NM_028410

RefSeq (protein)

NP_004696.2

NP_082686.1

Location (UCSC) Chr 11: 76.35 – 76.38 Mb Chr 7: 98.7 – 98.72 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

52 kDa repressor of the inhibitor of the protein kinase is an enzyme that in humans is encoded by the PRKRIR gene.[3][4]

Interactions

PRKRIR has been shown to interact with STK4[5] and DNAJC3.[3]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. 1 2 Gale M Jr; Blakely CM; Hopkins DA; Melville MW; Wambach M; Romano PR; Katze MG (Feb 1998). "Regulation of interferon-induced protein kinase PKR: modulation of P58IPK inhibitory function by a novel protein, P52rIPK". Mol Cell Biol. 18 (2): 859–71. doi:10.1128/mcb.18.2.859. PMC 108797Freely accessible. PMID 9447982.
  4. "Entrez Gene: PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)".
  5. Lin, Yenshou; Khokhlatchev Andrei; Figeys Daniel; Avruch Joseph (Dec 2002). "Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis". J. Biol. Chem. United States. 277 (50): 47991–8001. doi:10.1074/jbc.M202630200. ISSN 0021-9258. PMID 12384512.

Further reading


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