Polyamine-modulated factor 1

PMF1
Identifiers
Aliases	PMF1
External IDs	HomoloGene: 5224 GeneCards: PMF1
Gene ontology Molecular function • transcription coactivator activity • leucine zipper domain binding • protein binding Cellular component • chromosome • condensed chromosome kinetochore • cytosol • MIS12/MIND type complex • chromosome, centromeric region • nucleus • kinetochore • transcription factor complex • nucleoplasm Biological process • chromosome segregation • cell division • cell cycle • regulation of transcription, DNA-templated • mitotic nuclear division • transcription from RNA polymerase II promoter • transcription, DNA-templated • sister chromatid cohesion Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	11243	n/a
Ensembl	ENSG00000160783	n/a
UniProt	Q6P1K2	n/a
RefSeq (mRNA)	NM_007221 NM_001199653 NM_001199654	n/a
RefSeq (protein)	NP_001186582.1 NP_001186583.1 NP_001186590.1 NP_001186592.1 NP_009152.2	n/a
Location (UCSC)	Chr 1: 156.21 – 156.24 Mb	n/a
PubMed search	[1]	n/a
Wikidata

View/Edit Human

Polyamine-modulated factor 1 is a protein that in humans is encoded by the PMF1 gene.^[2][3]

Interactions

Polyamine-modulated factor 1 has been shown to interact with MIS12.^[4][5]

References

1. "Human PubMed Reference:".
2. Wang Y, Devereux W, Stewart TM, Casero RA Jr (Aug 1999). "Cloning and characterization of human polyamine-modulated factor-1, a transcriptional cofactor that regulates the transcription of the spermidine/spermine N(1)-acetyltransferase gene". J Biol Chem. 274 (31): 22095–101. doi:10.1074/jbc.274.31.22095. PMID 10419538.
3. "Entrez Gene: PMF1 polyamine-modulated factor 1".
4. Cheeseman, Iain M; Niessen Sherry; Anderson Scott; Hyndman Francie; Yates John R; Oegema Karen; Desai Arshad (Sep 2004). "A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension". Genes Dev. United States. 18 (18): 2255–68. doi:10.1101/gad.1234104. ISSN 0890-9369. PMC 517519. PMID 15371340.
5. Obuse, Chikashi; Iwasaki Osamu; Kiyomitsu Tomomi; Goshima Gohta; Toyoda Yusuke; Yanagida Mitsuhiro (Nov 2004). "A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1". Nat. Cell Biol. England. 6 (11): 1135–41. doi:10.1038/ncb1187. ISSN 1465-7392. PMID 15502821.

Further reading

• Wang Y, Devereux W, Stewart TM, Casero RA (2001). "Characterization of the interaction between the transcription factors human polyamine modulated factor (PMF-1) and NF-E2-related factor 2 (Nrf-2) in the transcriptional regulation of the spermidine/spermine N1-acetyltransferase (SSAT) gene". Biochem. J. 355 (Pt 1): 45–9. doi:10.1042/0264-6021:3550045. PMC 1221710. PMID 11256947.
• Wang Y, Devereux W, Stewart TM, Casero RA (2002). "Polyamine-modulated factor 1 binds to the human homologue of the 7a subunit of the Arabidopsis COP9 signalosome: implications in gene expression". Biochem. J. 366 (Pt 1): 79–86. doi:10.1042/BJ20020211. PMC 1222765. PMID 12020345.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Cheeseman IM, Niessen S, Anderson S, et al. (2004). "A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension". Genes Dev. 18 (18): 2255–68. doi:10.1101/gad.1234104. PMC 517519. PMID 15371340.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Obuse C, Iwasaki O, Kiyomitsu T, et al. (2004). "A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1". Nat. Cell Biol. 6 (11): 1135–41. doi:10.1038/ncb1187. PMID 15502821.
• Kline SL, Cheeseman IM, Hori T, et al. (2006). "The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation". J. Cell Biol. 173 (1): 9–17. doi:10.1083/jcb.200509158. PMC 2063780. PMID 16585270.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.