Progoitrin

Progoitrin

Identifiers
CAS Number	585-95-5
3D model (Jmol)	Interactive image
ChEBI	CHEBI:79352
InChI InChI=1S/C11H19NO10S2/c1-2-5(14)3-7(12-22-24(18,19)20)23-11-10(17)9(16)8(15)6(4-13)21-11/h2,5-6,8-11,13-17H,1,3-4H2,(H,18,19,20)/t5-,6+,8+,9-,10+,11-/m0/s1 Key: MYHSVHWQEVDFQT-ILPXZUKPSA-N
SMILES OC[C@H]1O[C@@H](SC(C[C@@H](O)C=C)=NOS(O)(=O)=O)[C@H](O)[C@@H](O)[C@@H]1O
Properties
Chemical formula	C11H19NO10S2
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Progoitrin is a biochemical from the glucosinolate family that is found in some food, which is inactive but after ingestion is converted to goitrin. Goitrin decrease the thyroid hormone production.

Progoitrin has been isolated in cabbage, brussels sprouts, kale, peanuts, mustard, rutabaga, kohlrabi, spinach, cauliflower, horseradish, and oil-seed rape.^[1]

References

1. Comprehensive Pharmacy Review, Leon Shargel, 6th edition, p1191.

Bibliography

• Greer, Monte A. (20 March 1956). "Isolation from Rutabaga Seed of Progoitrin, the Precursor of the Naturally Occurring Antithyroid Compound, Goitrin (L-5-Vinyl-2-Thioöxazolidine)¹". Journal of the American Chemical Society. 78 (6): 1260–1261. doi:10.1021/ja01587a052.