Revival Soy

Revival Soy is a brand of soy food and supplement products developed by Physicians Pharmaceuticals, Inc., a private, family-owned company located in Kernersville, North Carolina. Dr. Aaron Tabor, M.D. founded Physicians Pharmaceuticals in an effort to help his mother with the menopausal transition. He accomplished this goal by patenting a natural concentration process for soy that allowed Revival Soy to provide a higher amount of soy isoflavones than found in most soy products.[1]

Dr. Aaron Tabor

Aaron Tabor, M.D. is the CEO and Medical Research Director of Physicians Pharmaceuticals, Inc. A graduate of Wake Forest University and the Johns Hopkins School of Medicine, Dr. Tabor oversees all clinical research on Revival Soy products. He is also responsible for directing new Revival Soy product development based on clinical research results.

Dr. Tabor is on the Editorial Board for the Journal of Medicine, a personalized, peer-reviewed journal, as Section Editor for Integrated Medicine. He is also a member of various medical associations and health groups including the American Medical Association, North American Menopause Society, American Heart Association, American Diabetes Association, and National Consortium of Breast Centers among others.

History

Revival Soy originally began shipping products in 1998. Within two years of its establishment, Physicians Pharmaceuticals was shipping up to 7,000 shipments per month.[2] With the surge in soy protein interest associated with the FDA-approved soy protein heart health claim, Physicians Pharmaceuticals continued to see a rapid growth in their business.[3][4] Physicians Pharmaceuticals sold their one-millionth order of Revival Soy products on September 21, 2004.[5] As more soy food companies came into existence and the soy protein market began to mature, sales started to level out. In order to account for these changes in the market, Physicians Pharmaceuticals reduced staff in 2005.[6] Today, Physicians Pharmaceuticals, makers of Revival Soy products, remains a highly profitable company with a growing number of marketing partners.

Awards and recognition

Product Portfolio

Revival Soy sells a wide variety of soy protein bars and shakes, as well as a number of other complementary products, primarily direct to consumers through their website and call center.

Several of the Revival Soy products are low-glycemic. A selection of Revival Soy foods was tested using standardized glycemic index testing at an independent laboratory in Sydney, Australia.[9] This analysis demonstrated that all but one (the Baked Soy Protein Chips) of the foods tested had a low glycemic index; however, all the foods tested had a low to medium glycemic load. A number of health benefits have been attributed to low-glycemic diets.[10]

Health Research

Physicians Pharmaceuticals is an active participant in clinical research related to soy and human health. Revival Soy protein products have been used in multiple clinical research studies, including nearly twenty clinical trials that have been published in peer-reviewed scientific journals.[11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31] Research with Revival Soy products has demonstrated the benefits of soy for several aspects of human health including menopause, weight loss, skin health, and heart health.

In one double-blind, placebo-controlled study, postmenopausal women drank either Revival Soy protein shakes or placebo shakes daily for 3 months.[13] Using the Menopause-Specific Quality of Life (MENQOL) questionnaire, differences in vasomotor (hot flashes & night sweats), psychosocial (mood), physical (stamina, sleep, aches, etc.), and sexual (intimacy) symptoms were determined. The results of this study showed that on average the women consuming the Revival Soy shakes daily for just 12 weeks saw an improvement (~40% on average) in all 4 postmenopausal quality of life areas, including a reduction in hot flashes and night sweats. In contrast, the study volunteers in the placebo group did not obtain these benefits. The study investigators concluded that consuming Revival Soy was associated with an improved quality of life in early postmenopausal women.

Two recent studies have suggested that Revival Soy products can be an integral part of a healthy weight loss plan. In one study, overweight women (n=43) were asked to follow a low-energy diet (1,000–1,200 Calories/day) that included 3 shakes with 20 grams of milk protein or 20 grams of Revival Soy protein per day, one pre-packaged entrée, and at least 5 fruits and vegetable servings daily.[21] Compliance with this diet using either milk protein shakes or soy protein shakes resulted in significant weight loss and reductions in body fat. Average weight loss was approximately 26-29 pounds and did not differ significantly between groups. In a second study, overweight, postmenopausal women on a weight maintenance diet were asked to drink either a Revival Soy protein shake (20 g soy protein with 160 mg soy isoflavones) or a milk protein shake (20 g milk protein with no isoflavones) daily for 3 months.[19] Different measures of body fat were evaluated after 3 months. Despite being on a weight maintenance diet plan, total abdominal (belly) fat was reduced in the soy protein group and increased in the milk protein group. These results show that Revival Soy protein can be a highly effective part of a weight loss program.

A study conducted at Johns Hopkins University reported that Revival Soy protein shakes might support normal cholesterol health.[22] In this randomized, double-blind, placebo-controlled clinical trial, 216 postmenopausal women (~ 50% of whom were African-American) drank either Revival Soy protein shakes or milk protein shakes every day for 12 weeks. After 6 weeks, results from this study showed that consumption of Revival Soy protein shakes supported greater decreases in LDL-cholesterol concentration and LDL particle number than the milk protein shakes.

Research also has suggested that Revival Soy protein shakes might support healthy skin, hair, and nails.[20] A research study conducted by a board-certified dermatologist assigned postmenopausal women (50–65 years of age) with mild to moderate photoaging to drink either one Revival Soy protein shake or to remain on their normal diet for 6 months. After 6 months of dietary soy consumption, improvements were seen in facial wrinkling, discoloration, and overall appearance. Also, improvement was noted in nail roughness, ridging, flaking, splitting, and overall appearance at the end of the intervention period. Improvements in hair health were evident for roughness, manageability, and overall appearance after consuming soy for 3 months with additional improvements observed after 6 months in terms of hair roughness, dullness, and overall appearance. Similar benefits of Revival Soy protein have been reported for premenopausal women.[30]

Revival Soy products have also been used in studies where the potential health benefits of soy wert not being examined directly. One of the current hot topics in soy research is equol, an isoflavone made from one of the isoflavones in soy.[31] A number of clinical research trials have used Revival Soy foods to determine whether individuals consuming soy can make equol or not.[17][23][25][26][27][28][29] The absorption of isoflavones from Revival Soy products has also been examined with the results showing that isoflavones are readily absorbed from Revival Soy products,[12][15][16][18] though absorption was less from soy nuts than from bars and shakes.[12]

Philanthropic Endeavors

References

  1. ↑ USDA Database for the Isoflavone Content of Selected Foods, Release 2.0
  2. ↑ Sold on soy: family business booming. The Business Journal, January 28, 2000.
  3. 1 2 Business Journal recognizes fast-growing companies. The Business Journal, November 1, 2002
  4. ↑ Revival Soy already surpassing ’03 expectations. The Business Journal, May 2, 2003.
  5. ↑ Revival Soy ships millionth order. The Business Journal, September 21, 2004.
  6. ↑ Trimmed down Revival Soy collaborates with startup. The Business Journal, May 20, 2005.
  7. ↑ Kernersville chamber names small-business award winners. The Business Journal, May 16, 2002.
  8. ↑ Business Journal honors fast-growing companies. The Business Journal, September 26, 2003.
  9. ↑ Blair RM, Henley EC, Tabor A. Soy foods have low glycemic and insulin response indices in normal weight subjects. Nutrition Journal 2006; 5:35.
  10. ↑ Barclay AW, Petocz P, McMillan-Price J, Flood VM, Prvan T, Mitchell P, Brand-Miller JC. Glycemic index, glycemic load, and chronic disease risk–a meta-analysis of observational studies. American Journal of Clinical Nutrition 2008; 87:627-637.
  11. ↑ Wahner-Roedler DL, Thompson JM, Luedtke CA, King SM, Cha SS, Elkin PL, Bruce BK, Townsend CO, Bergeson J, Eickhoff A, Loehrer LL, Sood A, Bauer BA. Effect of dietary soy supplement on fibromyalgia symptoms: a randomized, double-blind, placebo controlled trial. Evidence-Based Complementary and Alternative Medicine 2009; (In Press).
  12. 1 2 3 Franke AA, Ashburn LA, Kakazu K, Suzuki S, Wilkens LR, Halm BM. Apparent bioavailability of isoflavones after intake of liquid and solid soya foods. British Journal of Nutrition 2009; (EPub ahead of print)
  13. 1 2 Basaria S, Wisniewski A, Dupree K, Bruno T, Sony MY, Yao F, Ojumu A, John M. Dobs AS. Effect of high-dose isoflavones on cognition, quality of life, androgens, and lipoprotein in post-menopausal women. J Endocrinol Invest 2009; 32:150-155.
  14. ↑ Charles C, Yuskavage J, Carlson O, John M, Tagalicud AS, Maggio M, Muller DC, Egan J, Basaria S. Effects of high-dose isoflavones on metabolic and inflammatory markers in healthy postmenopausal women. Menopause 2009; 16:395-400.
  15. 1 2 Franke AA, Halm BM, Ashburn LA. Urinary isoflavones are increased in adults, but decreased in children, consuming soy when on oral antibiotic therapy. Nutrition and Cancer 2008; 60:627-635.
  16. 1 2 Franke AA, Halm BM, Ashburn LA. Isoflavones in children and adults consuming soy. Archives of Biochemistry and Biophysics 2008; 476:161-170.
  17. 1 2 Fuhrman BJ, Teter BE, Barba M, Byrne C, Cavalleri A, Grant BJ, Horvath PJ, Morelli D, Venturelli E, Muti PC. Equol status modifies the association of soy intake and mammographic density in a sample of postmenopausal women. Cancer Epidemiology, Biomarkers & Prevention 2008; 17:33-42.
  18. 1 2 Halm BM, Ashburn LA, Franke AA. Isoflavones from soya foods are more bioavailable in children than adults. British Journal of Nutrition 2007; 8:998-1005.
  19. 1 2 Sites CK, Cooper BC, Toth MJ, Gastaldelli A, Arabshahi A, Barnes S. Effect of daily supplement of soy protein on body composition and insulin secretion in postmenopausal women. Fertility & Sterility 2007; 88:1609-17.
  20. 1 2 Draelos ZD, Blair R, Tabor A. Oral soy supplementation and dermatology. Cosmetic Dermatology 2007; 20:202-204.
  21. 1 2 Anderson JW, Fuller J, Patterson K, Blair R, Tabor A. Soy compared to casein meal replacement shakes with energy-restricted diets for obese women: randomized, controlled trial. Metabolism 2007; 56:280-288.
  22. 1 2 Allen JK, Becker DM, Kwiterovich PO, Lindenstruth KA, Curtis C. Effect of soy protein-containing isoflavones on lipoproteins in postmenopausal women. Menopause 2007; 14:106-114.
  23. 1 2 Song KB, Atkinson C, Frankenfeld CL, Jokela T, Wahala K, Thomas WK, Lampe JW. Prevalence of daidzein-metabolizing phenotypes differs between Caucasian and Korean American women and girls. Journal of Nutrition 2006; 136:1347-1351.
  24. ↑ Hulem R, Blair RM. The role of soy isoflavones in the management of postmenopausal symptoms. ADVANCE for Nurse Practitioners May 2006, pp. 33-38.
  25. 1 2 FrankenfeldCL, McTiernan A, Thomas WK, LaCroix K, McVarish L, Holt VL, Schwartz SM, Lampe JW. Postmenopausal bone mineral density in relation to soy isoflavone-metabolizing phenotypes. Maturitas 2006; 53:315-324.
  26. 1 2 Frankenfeld CL, Atkinson C, Thomas WK, Gonzalez A, Jokela T, Wahala K, Schwartz SM, Li SS, Lampe JW. High concordance of daidzein-metabolizing phenotypes in individuals measured 1 to 3 years apart. British Journal of Nutrition 2005; 94:873-876.
  27. 1 2 Frankenfeld CL, Atkinson C, Thomas WK, Goode EL, Gonzalez A, Jokela T, Wahala K, Schwartz SM, Li SS, Lampe JW. Familial correlations, segregation analysis, and nongenetic correlates of soy isoflavone-metabolizing phenotypes. Experimental Biology and Medicine 2004; 229:902-913.
  28. 1 2 Frankenfeld CL, McTiernan A, Aiello EJ, Thomas WK, LaCroix K, Schramm J, Schwartz SM, Holt VL, Lampe JW. Mammographic density in relation to daidzein-metabolizing phenotypes in overweight, postmenopausal women. Cancer Epidemiology, Biomarkers and Prevention 2004; 13(7):1156-1162.
  29. 1 2 Frankenfeld CL, McTiernan A, Tworoger SS, Atkinson C, Thomas WK, Stanczyk FZ, Marcovina SM, Weigle DS, Weiss NS, Holt VL, Schwartz SM, Lampe JW. Serum steroid hormones, sex hormone-binding globulin concentrations, and urinary hydroxylated estrogen metabolites in post-menopausal women in relation to daidzein-metabolizing phenotypes. Journal of Steroid Biochemistry and Molecular Biology 2004; 88:399-408.
  30. 1 2 Blair RM, Tabor A. The Beauty of Soy for Skin, Hair, and Nails. In: Nutritional Cosmetics: Beauty from Within, Tabor A, Blair RM (eds). William Andrew Applied Science Publishers/Elsevier, 2009, pp 441-468.
  31. 1 2 Setchell KDR, Brown NM, Lydeking-Olsen E. The clinical importance of the metabolite equol–a clue to the effectiveness of soy and its isoflavones. Journal of Nutrition 2002; 132:3577-3584.
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