Rubidium-82 chloride

Rubidium-82 chloride

Names
IUPAC name Rubidium-82 chloride
Systematic IUPAC name (^82Rb)Rubidium chloride
Identifiers
CAS Number	132486-03-4
3D model (Jmol)	Interactive image
ChemSpider	64457
KEGG	D05773
PubChem	71357
InChI InChI=1S/ClH.Rb/h1H;/q;+1/p-1/i;1-3 Key: FGDZQCVHDSGLHJ-RYDPDVNUSA-M
SMILES [Cl-].[82Rb+]
Properties
Chemical formula	ClRb
Molar mass	117.371 g mol^−1
Pharmacology
ATC code	V09GX04 (WHO)
Related compounds
Other cations	Caesium chloride Lithium chloride Potassium chloride Rubidium chloride Sodium chloride
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Rubidium-82 chloride is a form of rubidium chloride using a radioactive isotope of rubidium. It is marketed under the brand name Cardiogen-82 (Bracco Diagnostics) in the use of Myocardial perfusion imaging (imaging of the heart).^[1] It is rapidly taken up by heart muscle cells, and therefore can be used to identify regions of heart muscle that are receiving poor blood flow in a technique called PET perfusion imaging.^[2] The half-life of the rubidium-82 is only 1.27 minutes; it is normally produced at the place of use by rubidium generators.^[3]

References

1. Th Wackers, Frans J; Bruni, Wendy; Zaret, Barry L (2007-11-19). "Rubidium-82 Generator". Nuclear cardiology: the basics : how to set up and maintain a laboratory. ISBN 978-1-58829-924-6.
2. Ballinger, James R. (2009). "Integrating Cardiology for Nuclear Medicine Physicians": 379–385. doi:10.1007/978-3-540-78674-0_32. ISBN 978-3-540-78673-3. |chapter= ignored (help)
3. K. L. Gould et al. "Clinical feasibility of positron cardiac imaging without a cyclotron using generator-produced rubidium-82." Journal of the American College of Cardiology 1986;7:775-789.

Further reading

• Clarke, Michael J; Sadler, P. J (1999-06-15). Metallopharmaceuticals: Diagnosis and therapy. ISBN 978-3-540-65308-0. (Note: only about 1/2 page on Rb-generator)
• Alvarez-Diez, T; Dekemp, R; Beanlands, R; Vincent, J (1999). "Manufacture of strontium-82/rubidium-82 generators and quality control of rubidium-82 chloride for myocardial perfusion imaging in patients using positron emission tomography". Applied Radiation and Isotopes. 50 (6): 1015–23. doi:10.1016/S0969-8043(98)00170-5. PMID 10355104.
• Waters, S. L.; Curseys, B. M., eds. (1987). "The Strontium-82/rubidium-82 generator". International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes. 38 (3): 171–239.