SANT domain

In molecular biology, a SANT domain is a protein domain that allows many chromatin remodeling proteins to interact with histones.[1] The name SANT is an acronym standing for "Swi3, Ada2, N-Cor, and TFIIIB".[2] The SANT domain is highly conserved, and is similar to Myb DNA-binding domains.

References

  1. ↑ Horton, J. R.; Elgar, S. J.; Khan, S. I.; Zhang, X.; Wade, P. A.; Cheng, X. (2007). "Structure of the SANT domain from the Xenopus chromatin remodeling factor ISWI". Proteins: Structure, Function, and Bioinformatics. 67 (4): 1198–1202. doi:10.1002/prot.21352. PMC 2688785Freely accessible. PMID 17377988.
  2. ↑ Boyer, L. A.; Latek, R. R.; Peterson, C. L. (2004). "Opinion: The SANT domain: A unique histone-tail-binding module?". Nature Reviews Molecular Cell Biology. 5 (2): 158–163. doi:10.1038/nrm1314. PMID 15040448.
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