SEC14L1

SEC14L1
Identifiers
Aliases	SEC14L1, PRELID4A, SEC14L, SEC14 like lipid binding 1
External IDs	MGI: 1921386 HomoloGene: 37719 GeneCards: SEC14L1
Gene ontology Molecular function • RIG-I binding • protein binding • molecular function regulator Cellular component • cytoplasm • integral component of membrane • Golgi apparatus Biological process • negative regulation of signal transduction • innate immune response • negative regulation of RIG-I signaling pathway • choline transport • transport • immune system process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6397	74136
Ensembl	ENSG00000129657	ENSMUSG00000020823
UniProt	Q92503	A8Y5H7
RefSeq (mRNA)	NM_003003 NM_001039573 NM_001143998 NM_001143999 NM_001144001 NM_001204408 NM_001204410	NM_001166506 NM_001166507 NM_028777
RefSeq (protein)	NP_001034662.2 NP_001137470.1 NP_001137471.1 NP_001137473.1 NP_001191337.1 NP_001191339.1 NP_002994.3	NP_001159978.1 NP_001159979.1 NP_083053.2
Location (UCSC)	Chr 17: 77.09 – 77.22 Mb	Chr 11: 117.12 – 117.16 Mb
PubMed search	[1]	[2]
Wikidata

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View/Edit Mouse

SEC14-like protein 1 is a protein that in humans is encoded by the SEC14L1 gene.^[3][4]

The protein encoded by this gene belongs to the SEC14 cytosolic factor family. It has similarity to yeast SEC14 and to Japanese flying squid RALBP which suggests a possible role of the gene product in an intracellular transport system.^[4]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Chinen K, Takahashi E, Nakamura Y (Sep 1996). "Isolation and mapping of a human gene (SEC14L), partially homologous to yeast SEC14, that contains a variable number of tandem repeats (VNTR) site in its 3' untranslated region". Cytogenet Cell Genet. 73 (3): 218–23. doi:10.1159/000134342. PMID 8697811.
4. "Entrez Gene: SEC14L1 SEC14-like 1 (S. cerevisiae)".

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Kalikin LM, Bugeaud EM, Palmbos PL, et al. (2002). "Genomic characterization of human SEC14L1 splice variants within a 17q25 candidate tumor suppressor gene region and identification of an unrelated embedded expressed sequence tag.". Mamm. Genome. 12 (12): 925–9. doi:10.1007/s00335-001-2073-3. PMID 11707779.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.