SEC16A

SEC16A
Identifiers
Aliases	SEC16A, KIAA0310, SEC16L, p250, SEC16 homolog A, endoplasmic reticulum export factor
External IDs	MGI: 2139207 HomoloGene: 10533 GeneCards: SEC16A
Gene ontology Molecular function • protein binding Cellular component • cytoplasm • cytosol • Golgi membrane • Golgi apparatus • endoplasmic reticulum membrane • endoplasmic reticulum • membrane Biological process • protein transport • COPII vesicle coating • substantia nigra development • vesicle-mediated transport • endoplasmic reticulum organization • transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9919	227648
Ensembl	ENSG00000148396	ENSMUSG00000026924
UniProt	O15027	n/a
RefSeq (mRNA)	NM_001276418 NM_014866	NM_153125
RefSeq (protein)	NP_001263347.1 NP_055681.1	n/a
Location (UCSC)	Chr 9: 136.44 – 136.48 Mb	Chr 2: 26.41 – 26.45 Mb
PubMed search	[1]	[2]
Wikidata

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View/Edit Mouse

Protein transport protein Sec16A is a protein that in humans is encoded by the SEC16A gene.^[3][4]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Nagase T; Ishikawa K; Nakajima D; Ohira M; Seki N; Miyajima N; Tanaka A; Kotani H; Nomura N; Ohara O (Sep 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 4 (2): 141–50. doi:10.1093/dnares/4.2.141. PMID 9205841.
4. "Entrez Gene: KIAA0310 KIAA0310".

Further reading

• Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
• Iinuma T, Shiga A, Nakamoto K, et al. (2007). "Mammalian Sec16/p250 plays a role in membrane traffic from the endoplasmic reticulum". J. Biol. Chem. 282 (24): 17632–9. doi:10.1074/jbc.M611237200. PMID 17428803.
• Bhattacharyya D; Glick BS (2007). "Two Mammalian Sec16 Homologues Have Nonredundant Functions in Endoplasmic Reticulum (ER) Export and Transitional ER Organization". Mol. Biol. Cell. 18 (3): 839–49. doi:10.1091/mbc.E06-08-0707. PMC 1805085. PMID 17192411.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Watson P, Townley AK, Koka P, et al. (2007). "Sec16 Defines Endoplasmic Reticulum Exit Sites and is Required for Secretory Cargo Export in Mammalian Cells". Traffic. 7 (12): 1678–87. doi:10.1111/j.1600-0854.2006.00493.x. PMC 1761133. PMID 17005010.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
• Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Bonaldo MF; Lennon G; Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.