TRIM31

TRIM31
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2YSJ, 2YSL
Identifiers
Aliases	TRIM31, C6orf13, HCG1, HCGI, RNF, tripartite motif containing 31
External IDs	MGI: 2385051 HomoloGene: 17137 GeneCards: TRIM31
Gene ontology Molecular function • zinc ion binding • ligase activity • protein binding • metal ion binding Cellular component • cytoplasm • cytosol • intracellular • mitochondrion Biological process • positive regulation of sequence-specific DNA binding transcription factor activity • innate immune response • negative regulation of viral entry into host cell • regulation of viral release from host cell • protein ubiquitination • interferon-gamma-mediated signaling pathway • negative regulation of viral transcription Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	11074	224762
Ensembl	n/a	ENSMUSG00000058063
UniProt	Q9BZY9 Q2L6J1	Q8R0K2
RefSeq (mRNA)	NM_007028	NM_146077
RefSeq (protein)	NP_008959.3 NP_008959.3	NP_666189.1
Location (UCSC)	Chr 6: 30.1 – 30.11 Mb	Chr 17: 36.9 – 36.91 Mb
PubMed search	[1]	[2]
Wikidata

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Tripartite motif-containing protein 31 is a protein that in humans is encoded by the TRIM31 gene.^[3][4]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to both the cytoplasm and the nucleus. Its function has not been identified.^[4]

Interactions

TRIM31 has been shown to interact with TRIM23.^[3]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A (May 2001). "The tripartite motif family identifies cell compartments". EMBO J. 20 (9): 2140–51. doi:10.1093/emboj/20.9.2140. PMC 125245. PMID 11331580.
4. "Entrez Gene: TRIM31 tripartite motif-containing 31".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene. 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• el Kahloun A, Chauvel B, Mauvieux V, et al. (1993). "Localization of seven new genes around the HLA-A locus.". Hum. Mol. Genet. 2 (1): 55–60. doi:10.1093/hmg/2.1.55. PMID 8490624.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene. 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
• Hillman RT, Green RE, Brenner SE (2005). "An unappreciated role for RNA surveillance.". Genome Biol. 5 (2): R8. doi:10.1186/gb-2004-5-2-r8. PMC 395752. PMID 14759258.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer.". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674.
• Shiina T, Ota M, Shimizu S, et al. (2006). "Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.". Genetics. 173 (3): 1555–70. doi:10.1534/genetics.106.057034. PMC 1526686. PMID 16702430.