TTC1

TTC1
Identifiers
Aliases	TTC1, TPR1, tetratricopeptide repeat domain 1
External IDs	MGI: 1914077 HomoloGene: 2485 GeneCards: TTC1
Gene ontology Molecular function • unfolded protein binding • protein binding Cellular component • cytoplasm • peroxisomal membrane Biological process • protein folding Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	7265	66827
Ensembl	ENSG00000113312	ENSMUSG00000041278
UniProt	Q99614	Q91Z38
RefSeq (mRNA)	NM_003314 NM_001282500	NM_133795
RefSeq (protein)	NP_001269429.1 NP_003305.1	NP_598556.1
Location (UCSC)	Chr 5: 160.01 – 160.07 Mb	Chr 11: 43.73 – 43.75 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Tetratricopeptide repeat protein 1 is a protein that in humans is encoded by the TTC1 gene.^[3][4]

Interactions

TTC1 has been shown to interact with HSPA4.^[5]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Murthy AE, Bernards A, Church D, Wasmuth J, Gusella JF (Nov 1996). "Identification and characterization of two novel tetratricopeptide repeat-containing genes". DNA Cell Biol. 15 (9): 727–35. doi:10.1089/dna.1996.15.727. PMID 8836031.
4. "Entrez Gene: TTC1 tetratricopeptide repeat domain 1".
5. Oh, Won-Kyung; Song Jaewhan (Aug 2003). "Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation". Mol. Cells. Korea (South). 16 (1): 84–91. ISSN 1016-8478. PMID 14503850.

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Marty C, Browning DD, Ye RD (2003). "Identification of tetratricopeptide repeat 1 as an adaptor protein that interacts with heterotrimeric G proteins and the small GTPase Ras". Mol. Cell. Biol. 23 (11): 3847–58. doi:10.1128/MCB.23.11.3847-3858.2003. PMC 155206. PMID 12748287.
• Oh WK, Song J (2004). "Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation". Mol. Cells. 16 (1): 84–91. PMID 14503850.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.