WNT2B

WNT2B
Identifiers
Aliases WNT2B, WNT13, Wnt family member 2B
External IDs MGI: 1261834 HomoloGene: 22526 GeneCards: WNT2B
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

7482

22414

Ensembl

ENSG00000134245

ENSMUSG00000027840

UniProt

Q93097

O70283

RefSeq (mRNA)

NM_024494
NM_001291880
NM_004185

NM_009520

RefSeq (protein)

NP_001278809.1
NP_004176.2
NP_078613.1

NP_033546.2

Location (UCSC) Chr 1: 112.47 – 112.53 Mb Chr 3: 104.95 – 104.96 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Protein Wnt-2b (formerly Wnt13[3]) is a protein that in humans is encoded by the WNT2B gene.[4][5][6]

This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis. This gene produces two alternative transcript variants.[6]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Kubo F, Takeichi M, Nakagawa S (2003). "Wnt2b controls retinal cell differentiation at the ciliary marginal zone". Development (Cambridge, England). 130 (3): 587–98. PMID 12490564.
  4. Katoh M, Hirai M, Sugimura T, Terada M (Oct 1996). "Cloning, expression and chromosomal localization of Wnt-13, a novel member of the Wnt gene family". Oncogene. 13 (4): 873–6. PMID 8761309.
  5. Katoh M, Kirikoshi H, Saitoh T, Sagara N, Koike J (Sep 2000). "Alternative splicing of the WNT-2B/WNT-13 gene". Biochem Biophys Res Commun. 275 (1): 209–16. doi:10.1006/bbrc.2000.3252. PMID 10944466.
  6. 1 2 "Entrez Gene: WNT2B wingless-type MMTV integration site family, member 2B".

Further reading


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