7-Dimethylallyltryptophan synthase

7-dimethylallyltryptophan synthase (EC 2.5.1.80, 7-DMATS) is an enzyme with systematic name dimethylallyl-diphosphate:L-tryptophan 7-dimethylallyltransferase.^[1]^[2] This enzyme catalyses the following chemical reaction

\rightleftharpoons

diphosphate + 7-(3-methylbut-2-enyl)-L-tryptophan

This enzyme is more flexible towards the aromatic substrate than EC 2.5.1.34 (4-dimethylallyltryptophan synthase).

References

↑ Kremer, A.; Li, S.M. (2008). "Potential of a 7-dimethylallyltryptophan synthase as a tool for production of prenylated indole derivatives". Appl. Microbiol. Biotechnol. 79 (6): 951–961. doi:10.1007/s00253-008-1505-3. PMID 18481055.
↑ Kremer, A.; Westrich, L.; Li, S.M. (2007). "A 7-dimethylallyltryptophan synthase from Aspergillus fumigatus: overproduction, purification and biochemical characterization". Microbiology. 153 (Pt 10): 3409–3416. doi:10.1099/mic.0.2007/009019-0. PMID 17906140.

Transferases: alkyl and aryl (EC 2.5)

2.5.1	Dimethylallyltranstransferase Thiaminase I Methionine adenosyltransferase Riboflavin synthase Dihydropteroate synthase Spermidine synthase Glutathione S-transferase Farnesyl-diphosphate farnesyltransferase Spermine synthase Alkylglycerone phosphate synthase Farnesyltransferase Geranylgeranyltransferase type 1 Porphobilinogen deaminase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

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