All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific)
| All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.84 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) (EC 2.5.1.84, nonaprenyl diphosphate synthase, solanesyl diphosphate synthase, SolPP synthase, SPP-synthase, SPP synthase, solanesyl-diphosphate synthase, OsSPS2) is an enzyme with systematic name geranyl-diphosphate:isopentenyl-diphosphate transtransferase (adding 7 isopentenyl units).[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- geranyl diphosphate + 7 isopentenyl diphosphate 7 diphosphate + all-trans-nonaprenyl diphosphate
This enzyme is involved in the synthesis of the side chain of menaquinone-9.
References
- ↑ Sagami, H.; Ogura, K.; Seto, S. (1977). "Solanesyl pyrophosphate synthetase from Micrococcus lysodeikticus". Biochemistry. 16: 4616–4622. doi:10.1021/bi00640a014. PMID 911777.
- ↑ Fujii, H.; Sagami, H.; Koyama, T.; Ogura, K.; Seto, S.; Baba, T.; Allen, C.M. (1980). "Variable product specificity of solanesyl pyrophosphate synthetase". Biochem. Biophys. Res. Commun. 96: 1648–1653. doi:10.1016/0006-291X(80)91363-7. PMID 7447947.
- ↑ Ohara, K.; Sasaki, K.; Yazaki, K. (2010). "Two solanesyl diphosphate synthases with different subcellular localizations and their respective physiological roles in Oryza sativa". J. Exp. Bot. 61 (10): –. doi:10.1093/jxb/erq103. PMID 20421194.
- ↑ Ohnuma, S.; Koyama, T.; Ogura, K. (1991). "Purification of solanesyl-diphosphate synthase from Micrococcus luteus. A new class of prenyltransferase". J. Biol. Chem. 266 (35): 23706–23713. PMID 1748647.
- ↑ Gotoh, T.; Koyama, T.; Ogura, K. (1992). "Farnesyl diphosphate synthase and solanesyl diphosphate synthase reactions of diphosphate-modified allylic analogs: the significance of the diphosphate linkage involved in the allylic substrates for prenyltransferase". J. Biochem. 112 (1): 20–27. PMID 1429508.
- ↑ Teclebrhan, H.; Olsson, J.; Swiezewska, E.; Dallner, G. (1993). "Biosynthesis of the side chain of ubiquinone:trans-prenyltransferase in rat liver microsomes". J. Biol. Chem. 268 (31): 23081–23086. PMID 8226825.
External links
- All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) at the US National Library of Medicine Medical Subject Headings (MeSH)
This article is issued from Wikipedia - version of the 5/16/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.