Arsenate-mycothiol transferase

Arsenate-mycothiol transferase (EC 2.8.4.2, ArsC1, ArsC2, mycothiol:arsenate transferase) is an enzyme with systematic name mycothiol:arsenate S-arsenotransferase.^[1] This enzyme catalyses the following chemical reaction

\rightleftharpoons

arseno-mycothiol + H₂O

Reduction of arsenate is part of a defence mechanism of the cell against toxic arsenate.

References

↑ Ordonez, E.; Van Belle, K.; Roos, G.; De Galan, S.; Letek, M.; Gil, J.A.; Wyns, L.; Mateos, L.M.; Messens, J. (2009). "Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange". J. Biol. Chem. 284: 15107–15116. doi:10.1074/jbc.m900877200. PMID 19286650.

Transferases: sulfur-containing group (EC 2.8)

2.8.1: Sulfurtransferases	Thiosulfate sulfurtransferase Rhodanese 3-mercaptopyruvate sulfurtransferase thiosulfate—thiol sulfurtransferase tRNA sulfurtransferase thiosulfate—dithiol sulfurtransferase biotin synthase cysteine desulfurase

2.8.2: Sulfotransferases	Alcohol sulfotransferase Tyrosylprotein sulfotransferase Aryl sulfotransferase

2.8.3: CoA-transferases	Propionate CoA-transferase

2.8.4: Alkylthio	Coenzyme-B sulfoethylthiotransferase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

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