Butyrate—acetoacetate CoA-transferase
| butyrate-acetoacetate CoA-transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.8.3.9 | ||||||||
| CAS number | 66231-37-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
| |||||||||
In enzymology, a butyrate-acetoacetate CoA-transferase (EC 2.8.3.9) is an enzyme that catalyzes the chemical reaction
- butanoyl-CoA + acetoacetate butanoate + acetoacetyl-CoA
Thus, the two substrates of this enzyme are butanoyl-CoA and acetoacetate, whereas its two products are butanoate and acetoacetyl-CoA.
This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is butanoyl-CoA:acetoacetate CoA-transferase. Other names in common use include butyryl coenzyme A-acetoacetate coenzyme A-transferase, and butyryl-CoA-acetoacetate CoA-transferase.
References
- Barker HA, Jeng IM, Neff N, Robertson JM, Tam FK, Hosaka S (1978). "Butyryl-CoA:acetoacetate CoA-transferase from a lysine-fermenting Clostridium". J. Biol. Chem. 253 (4): 1219–25. PMID 624727.
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