Cephalosporin-C transaminase

Thus, the two substrates of this enzyme are (7R)-7-(5-carboxy-5-oxopentanoyl)aminocephalosporinate and D-glutamate, whereas its two products are cephalosporin C and 2-oxoglutarate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is cephalosporin-C:2-oxoglutarate aminotransferase. Other names in common use include cephalosporin C aminotransferase, and L-alanine:cephalosporin-C aminotransferase. This enzyme participates in penicillin and cephalosporin biosynthesis.

References

Aretz W, Sauber K (1988). "Novel D-amino acid transaminase". Ann. N. Y. Acad. Sci. 542: 366–70. PMID 3228235.

Transferase: nitrogenous groups (EC 2.6)

2.6.1: Transaminases	Aspartate transaminase GOT1 GOT2 Alanine transaminase GABA transaminase Tyrosine aminotransferase Ornithine aminotransferase Branched chain aminotransferase Alanine—glyoxylate transaminase AGXT

2.6.3: Oximinotransferases	Oximinotransferase

2.6.99: Other	Pyridoxine 5'-phosphate synthase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

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